Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Treatment of Kynurenin-producing Tumors with AhR Antagonists

23.11.2012
Activation of the aryl hydrocarbon receptor (AHR) by environmental xenobiotic toxins has been implicated in a variety of cellular processes such as embryogenesis, transformation, tumorigenesis and inflammation. The TDO-AHR pathway is active in human brain tumors and associated with malignant progression and poor survival. As Kyn is produced during cancer progression and inflammation in the local microenvironment in amounts sufficient for activating the human AHR, these results can be used to develop a specific chemotherapy to manipulate AhR activated signal pathways in susceptible cancer cells. Using this mechanism more treatment opportunities can be used and different tumor types can be treated by AhR related drugs.

Further Information: PDF

Deutsches Krebsforschungszentrum DKFZ
Phone: +49-6221-42 2955

Contact
Dr. Ruth Herzog

info@technologieallianz.de | TechnologieAllianz e.V.
Further information:
http://www.technologieallianz.de/angebote.php?sort=sag&id=2985&lang=en
http://www.technologieallianz.de

More articles from Technology Offerings:

nachricht Synthesis of novel Myrtucommulone and Analogues
25.11.2013 | TechnologieAllianz e.V.

nachricht Transmission signal separation in radar systems for OFDM and multicarrier radar
22.11.2013 | TechnologieAllianz e.V.

All articles from Technology Offerings >>>

The most recent press releases about innovation >>>

Anzeige

Anzeige

Event News

IT security in the digital society

27.08.2014 | Event News

Understanding the brain—neuroscientists meet in Göttingen

27.08.2014 | Event News

MEDICA EDUCATION CONFERENCE: Bessere Behandlung dank Biomarker

21.08.2014 | Event News

 
Latest News

A smart fluorescent antenna for Wi-Fi applications

02.09.2014 | Power and Electrical Engineering

Blowfly maggots provide physical evidence for forensic cases

02.09.2014 | Life Sciences

Single laser stops molecular tumbling motion instantly

02.09.2014 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>