Genetic coding of electron spin resonance markers

Electron spin resonance (ESR) spectroscopy provides data about the structure and dynamics of large molecules and permits the examination of biologically-relevant systems, which play a role in the regulation of the expression of illness-related genes. However, magnetic markings must be affixed to strategically-selected points of protein structures, because most biological structures do not contain unpaired electrons.
At the University of Konstanz, a molecular structure and the corresponding process were developed, with which the incorporation of ESR markers into peptide structures are largely independent of existing amino acid residues. The incorporation of the markers can be done specifically in any protein structure. The peptide structure experiences no essential changes, which makes an examination using ESR spectroscopy possible in intracellular and in vivo fashion.

Further information: PDF

Technologie-Lizenz-Büro (TLB) der Baden-Württembergischen Hochschulen GmbH
Phone: +49 (0)721/79 00 40

Contact
Dipl.-Biol. Marcus Lehnen, MBA

As Germany's association of technology- and patenttransfer agencies TechnologieAllianz e.V. is offering businesses access to the entire range of innovative research results of almost all German universities and numerous non-university research institutions. More than 2000 technology offers of 14 branches are beeing made accessable to businesses in order to assure your advance on the market. At www.technologieallianz.de a free, fast and non-bureaucratic access to all further offers of the German research landscape is offered to our members aiming to sucessfully transfer technologies.

Media Contact

info@technologieallianz.de TechnologieAllianz e.V.

All latest news from the category: Technology Offerings

Back to home

Comments (0)

Write a comment

Newest articles

Cooling down solar cells, naturally

Photovoltaics are more efficient when they operate at lower temperatures, which can be achieved in solar farms that space out arrays and use the wind to their advantage. A bright,…

Strongest Arctic cyclone on record led to surprising loss of sea ice

A warming climate is causing a decline in sea ice in the Arctic Ocean, where loss of sea ice has important ecological, economic and climate impacts. On top of this…

Tuberculosis and COVID-19 lung lesions

… revealed by high-resolution three-dimensional imaging. Insights that are not possible with conventional two-dimensional platforms include characterization of obliterated airways in tuberculosis and hemorrhage from ruptured blood vessels in COVID-19…

Partners & Sponsors