Early Therapy of Cystic Fibrosis (CF)

At present only the symptoms of the hereditary disease CF, which results in death at a young age, are being treated, not the actual cause. The novel preventive therapeutic strategy consists of an early treatment of CF before any disease-specific symptoms can be detected. In animal trials the early therapy with sodium channel blocker amiloride, commencing immediately after birth, prevents the development of CF. Clinical trials of amiloride as an early intervention preventive therapy against CF are already in the planning phase.

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