Cyplat – Ortho-platinated Primary Amines

The invention pertains to a new method for the synthesis

of organometallic platinum(II) complexes with orthoplatinated primary amines as ligands. The procedure developed in this context provides the first high-yield and general access to the title compounds. The compounds obtained according to this new synthetic route represent potential candidates for the medical treatment of tumor diseases. Results on cell cultures are available and indicate pronounced cytotoxicity in pharmacologically relevant concent rations.

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