Features: Specific implementation in the vascular system, high capacity for the incorporation of foreign DNA, not toxic to patients, high transfer efficiency, easy to handle. Tumourigenic processes and the formation of metastases crucially depend on angiogenesis. Angiogenesis in tumour tissue is stimulated, among other things, by tumour-specific factors. Among them are growth factors, such as the 'Fibroblast Growth Factor' (FGF) and the 'Vascular Endothelial Growth Factor' (VEGF). For some time, therapy concepts have been under development which are aimed specifically at the prevention of the vascular supply of tumours. A newer strategy is the specific interference with the structure and function of the tumour endothelium in order to prevent the blood supply of the tumour in the end. Herein, gene transfer systems play an important role. With them, the targeted expression of certain proteins in the tumour endothelium via specific targeting or, in contrast, specifically regulated expression becomes possible.
email@example.com | TechnologieAllianz e.V.
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Scientists at the Fraunhofer Institute for Laser Technology ILT have come up with a striking new addition to contact stamping technologies in the ERDF research project ScanCut. In collaboration with industry partners from North Rhine-Westphalia, the Aachen-based team of researchers developed a hybrid manufacturing process for the laser cutting of thin-walled metal strips. This new process makes it possible to fabricate even the tiniest details of contact parts in an eco-friendly, high-precision and efficient manner.
Plug connectors are tiny and, at first glance, unremarkable – yet modern vehicles would be unable to function without them. Several thousand plug connectors...
An international research team has found a new approach that may be able to reduce bone loss in osteoporosis and maintain bone health.
Osteoporosis is the most common age-related bone disease which affects hundreds of millions of individuals worldwide. It is estimated that one in three women...
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“Core-shell” clusters pave the way for new efficient nanomaterials that make catalysts, magnetic and laser sensors or measuring devices for detecting electromagnetic radiation more efficient.
Whether in innovative high-tech materials, more powerful computer chips, pharmaceuticals or in the field of renewable energies, nanoparticles – smallest...
An international research team with Prof. Cornelia Denz from the Institute of Applied Physics at the University of Münster develop for the first time light fields using caustics that do not change during propagation. With the new method, the physicists cleverly exploit light structures that can be seen in rainbows or when light is transmitted through drinking glasses.
Modern applications as high resolution microsopy or micro- or nanoscale material processing require customized laser beams that do not change during...
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