New animal knock-out system to study dysfunction of chondrocytes
Arthritic diseases are conditions involving damages to the joints and/or cartilage, mostly due to dysfunction of chondrocytes. Osteoarthritis is the most common form of arthritis, which affects over 200 million people worldwide. The pharmaceutical market for arthritis generated $15.9 billion in revenues in 2008. Scientists of the University of Göttingen have now developed a new animal drug screening model for arthritic diseases, which is caused by dysfunction of the Hedgehog pathway specifically in chondrocytes.
Further Information: PDF
MBM ScienceBridge GmbH
Phone: (0551) 30724-151
Contact
Dr. Jens-Peter Horst
Media Contact
All latest news from the category: Technology Offerings
Newest articles
High-energy-density aqueous battery based on halogen multi-electron transfer
Traditional non-aqueous lithium-ion batteries have a high energy density, but their safety is compromised due to the flammable organic electrolytes they utilize. Aqueous batteries use water as the solvent for…
First-ever combined heart pump and pig kidney transplant
…gives new hope to patient with terminal illness. Surgeons at NYU Langone Health performed the first-ever combined mechanical heart pump and gene-edited pig kidney transplant surgery in a 54-year-old woman…
Biophysics: Testing how well biomarkers work
LMU researchers have developed a method to determine how reliably target proteins can be labeled using super-resolution fluorescence microscopy. Modern microscopy techniques make it possible to examine the inner workings…