Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Heart disease associated with oral health – studies of women and serological factors

20.02.2004


A new study from Karolinska Institutet in Sweden shows, for the first time, an association between coronary heart disease and oral health in women. Recent results have also shown that serological factors, might provide insight into the reported epidemiological association between periodontitis and cardiovascular disease.



Cardiovascular disease (CVD) is the leading cause of death in the Western industrialized world. Classic risk factors such as smoking, obesity and high blood lipids do not explain all clinical and epidemiological features of CVD. Chronic inflammation has been suggested as a possible “unknown” risk factor. However, the chronic inflammatory disease periodontitis, has only recently been found to be associated to CVD.

A new study from Karolinska Institutet shows, for the first time, an association between coronary heart disease (CHD) and oral health in women. A group of 187 female patients with CHD had fewer remaining teeth (P<0.001) and more pathological periodontal pockets (P=0.002) compared to a control group. Dentures were more frequent (27% vs. 6%) as was edentulousness (10.5% vs. 0%) in the CHD group compared to the controls.


In another recent study from Karolinska Institutet risk factors for CVD were found in plasma from patients with periodontitis. Plasma levels of markers for arteriosclerosis and indices of inflammation in 50 patients with severe periodontitis were compared with those in 46 healthy cases. Total cholesterol levels were similar in the two groups, whereas levels of high density lipoproteins (HDL) were lower (P=0.007) and levels of C-reactive protein (CRP) were higher in the patient group. This is important, as both HDL and CRP are accepted risk factors for arteriosclerosis. Plasma levels of bacterial antigen specific IgA anti-Hsp60 antibodies were also lower in the patient group (P=0.0001). These serological differences might provide insight into the reported epidemiological association between periodontitis and CVD.

A possible mechanism behind the reported association could be the release of bacteria, bacterial products or pro-inflammatory cytokines from the periodontal lesions into the blood stream.

Ulla Bredberg Rådén | alfa
Further information:
http://www.ki.se

More articles from Health and Medicine:

nachricht New method uses just a drop of blood to monitor lung cancer treatment
19.10.2018 | Osaka University

nachricht Photoactive bacteria bait may help in fight against MRSA infections
12.10.2018 | Purdue University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Goodbye, silicon? On the way to new electronic materials with metal-organic networks

Scientists at the Max Planck Institute for Polymer Research (MPI-P) in Mainz (Germany) together with scientists from Dresden, Leipzig, Sofia (Bulgaria) and Madrid (Spain) have now developed and characterized a novel, metal-organic material which displays electrical properties mimicking those of highly crystalline silicon. The material which can easily be fabricated at room temperature could serve as a replacement for expensive conventional inorganic materials used in optoelectronics.

Silicon, a so called semiconductor, is currently widely employed for the development of components such as solar cells, LEDs or computer chips. High purity...

Im Focus: Storage & Transport of highly volatile Gases made safer & cheaper by the use of “Kinetic Trapping"

Augsburg chemists present a new technology for compressing, storing and transporting highly volatile gases in porous frameworks/New prospects for gas-powered vehicles

Storage of highly volatile gases has always been a major technological challenge, not least for use in the automotive sector, for, for example, methane or...

Im Focus: Disrupting crystalline order to restore superfluidity

When we put water in a freezer, water molecules crystallize and form ice. This change from one phase of matter to another is called a phase transition. While this transition, and countless others that occur in nature, typically takes place at the same fixed conditions, such as the freezing point, one can ask how it can be influenced in a controlled way.

We are all familiar with such control of the freezing transition, as it is an essential ingredient in the art of making a sorbet or a slushy. To make a cold...

Im Focus: Micro energy harvesters for the Internet of Things

Fraunhofer IWS Dresden scientists print electronic layers with polymer ink

Thin organic layers provide machines and equipment with new functions. They enable, for example, tiny energy recuperators. In future, these will be installed...

Im Focus: Dynamik einzelner Proteine

Neue Messmethode erlaubt es Forschenden, die Bewegung von Molekülen lange und genau zu verfolgen

Das Zusammenspiel aus Struktur und Dynamik bestimmt die Funktion von Proteinen, den molekularen Werkzeugen der Zelle. Durch Fortschritte in der...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Conference to pave the way for new therapies

17.10.2018 | Event News

Berlin5GWeek: Private industrial networks and temporary 5G connectivity islands

16.10.2018 | Event News

5th International Conference on Cellular Materials (CellMAT), Scientific Programme online

02.10.2018 | Event News

 
Latest News

Nanocages in the lab and in the computer: how DNA-based dendrimers transport nanoparticles

19.10.2018 | Life Sciences

Thin films from Braunschweig on the way to Mercury

19.10.2018 | Physics and Astronomy

App-App-Hooray! - Innovative Kits for AR Applications

19.10.2018 | Trade Fair News

VideoLinks
Science & Research
Overview of more VideoLinks >>>