Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Video games lead to new paths to treat cancer, other diseases

16.02.2012
The cure for cancer comes down to this: video games.

In a research lab at Wake Forest University, biophysicist and computer scientist Samuel Cho uses graphics processing units (GPUs), the technology that makes videogame images so realistic, to simulate the inner workings of human cells.

"If it wasn't for gamers who kept buying these GPUs, the prices wouldn't have dropped, and we couldn't have used them for science," Cho says.

Now he can see exactly how the cells live, divide and die.

And that, Cho says, opens up possibilities for new targets for tumor-killing drugs.

Cho's most recent computer simulation, of a critical RNA molecule that is a component of the human telomerase enzyme, for the first time shows hidden states in the folding and unfolding of this molecule, giving scientists a far more accurate view of how it functions. The results of his research appear in the Journal of the American Chemical Society. Cho worked with colleagues from the University of Maryland and Zhejiang University in China for this study.

The human telomerase enzyme is found only in cancerous cells. It adds tiny molecules called telomeres to the ends of DNA strands when cells divide – essentially preventing cells from dying.

"The cell keeps reproducing over and over, and that's the very definition of cancer," Cho says. "By knowing how telomerase folds and functions, we provide a new area for researching cancer treatments."

A new drug would stop the human telomerase enzyme from adding onto the DNA, so the tumor cell dies.

Cho, an assistant professor of physics and computer science, has turned his attention to videogaming technology and the bacterial ribosome – a molecular system 200 times larger than the human telomerase enzyme RNA molecule. His research group has begun to use graphics cards called GPUs to perform these cell simulations, which is much faster than using standard computing.

"We have hijacked this technology to perform simulations very, very quickly on much larger biomolecular systems," Cho says.

Without the GPUs, Cho estimated it would have taken him more than 40 years to program that simulation.

Now, it will take him a few months.

About Wake Forest University

Wake Forest University combines the best traditions of a small liberal arts college with the resources of a large research university. Founded in 1834, the school is located in Winston-Salem, N.C. The University's graduate school of arts and sciences, divinity school, and nationally ranked schools of law, medicine and business enrich our intellectual environment. Learn more about Wake Forest University at www.wfu.edu

Katie Neal | EurekAlert!
Further information:
http://www.wfu.edu

Further reports about: DNA DNA strand RNA RNA molecule human cell molecular system telomerase enzyme

More articles from Life Sciences:

nachricht Microscope measures muscle weakness
16.11.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

nachricht Good preparation is half the digestion
16.11.2018 | Max-Planck-Institut für Stoffwechselforschung

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

Im Focus: Penn engineers develop ultrathin, ultralight 'nanocardboard'

When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure

Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

European Space Talks: Weltraumschrott – eine Gefahr für die Gesellschaft?

23.10.2018 | Event News

 
Latest News

Purdue cancer identity technology makes it easier to find a tumor's 'address'

16.11.2018 | Health and Medicine

Good preparation is half the digestion

16.11.2018 | Life Sciences

Microscope measures muscle weakness

16.11.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>