There sits in most mammalian cells what amounts to a lock-box of DNA tucked away from the bulk of genetic material. While scientists routinely cut and paste snippets of lifes blueprint to learn more about life and to treat disease, crucial DNA within cellular structures known as mitochondria has remained off-limits.
Thats beginning to change, though, thanks in part to work described in the Feb. 10 issue of the Proceedings of the National Academy of Sciences by a team from the University of Rochester Medical Center and the University of Melbourne in Australia. Scientists created a new kind of mouse by replacing the genetic material in the mitochondria of one species with that from another in a gene-swapping exercise necessary if doctors are to understand several currently untreatable human diseases.
"What we call mitochondrial medicine – how specific mitochondrial mutations and deficiencies lead to disease – didnt even exist 15 years ago. Now the field is in its infancy. The ultimate goal is improved treatment for people with disorders that currently cant be treated," says Carl A. Pinkert, Ph.D., of the Center for Aging and Developmental Biology at Rochester, who led the Rochester team.
Tom Rickey | EurekAlert!
New way to look at cell membranes could change the way we study disease
19.11.2018 | University of Oxford
Controlling organ growth with light
19.11.2018 | European Molecular Biology Laboratory
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
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19.11.2018 | Life Sciences