Personalized treatment of Era-positive breast cancer: Validation of a protein biomarker set that identifies patients requiring chemotherapy

70-80% of newly diagnosed breast tumors account for hormone receptor positive breast cancer (also known as luminal breast cancer). The histologic grade of luminal breast cancer is often determined by semi-quantitative methods describing morphologic features related to the differentiation states of the tumor specimen. In order to make a clear-cut classification of luminal breast cancer as either “grade 1” (= low risk) or “grade 3” (= high risk) tumors, DKFZ researchers have developed a 3-protein marker set.

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DKFZ (German Cancer Research Center, Deutsches Krebsforschungszentrum)
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Dr. Ruth Herzog

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