Optical Tomography (OT) and MR combination for dual-modality imaging
Optical techniques, such as bioluminescence and fluorescence, are emerging as powerful new modalities for molecular imaging in disease and therapy. Combining innovative molecular biology and chemistry, researchers have developed optical methods for imaging a variety of cellular and molecular processes in vivo, including protein interactions, protein degradation, and protease activity.
DKFZ developed an optical imaging detector regarding fluorescence and bioluminescence for small animal imaging, which is compatible for magnetic resonance imaging (MRI). This technology provides the possibility to study simultaneously tracer/marker kinetics of optical (OT) as well as NMR induced signals.
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