Interferons play a vital role in the natural response on viral infection. In particular, type I interferon (IFN-I) is the focus of interest in the development of new therapeutic approaches for example in the fields of immunology, tumor diseases, multiple sclerosis and sepsis. </p> <strong>Technology</strong><br> Two novel transgenic mice have been developed, the IFNAR knock-out mouse (IFNARKO) and the conditional IFNAR mouse (IFNARCOND), both congenic on the C57BL/6 background, the mouse type from which most of the tumors used in tumor models are isolated. The IFNARKO mouse carries an ubiquitous deletion of the interferon type I receptor (IFNAR) allowing investigations into the role of IFNAR in every tissue and every stage of development. The conditional IFNAR-mouse allows the potential IFNAR inactivation by an adequate stimulus in a specific tissue or cell type. By this, the function of the IFN-I system can be investigated in its spatial and temporal dimensions for the first time by targeted time- and/or site-controlled IFNAR inactivation.<br><br>
firstname.lastname@example.org | TechnologieAllianz e.V.
New Lithium Salts of Pentafluorophenylamide Anions as Electrolytes in Lithium Ionic Batteries
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On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.
We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
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