Screening and Model Systems for Therapies of Alzheimer Disease (AD)
A new strategy for the therapy of AD describes that moderate enhancement of the α-secretase ADAM10 completely inhibits amyloid plaque deposition and enhances the production of the N-terminal domain of the amyloid precursor protein (APP), that acts as neuropotective component. As a consequence, these effects improve synaptic plasticity and reduces cognitive defects shown in a transgenic mouse model for AD.
Further Information: PDF
IMG Innovations-Management GmbH
Phone: +49 (0)631/31668-0
Contact
Dr. Klaus Kobek
Media Contact
All latest news from the category: Technology Offerings
Newest articles
High-energy-density aqueous battery based on halogen multi-electron transfer
Traditional non-aqueous lithium-ion batteries have a high energy density, but their safety is compromised due to the flammable organic electrolytes they utilize. Aqueous batteries use water as the solvent for…
First-ever combined heart pump and pig kidney transplant
…gives new hope to patient with terminal illness. Surgeons at NYU Langone Health performed the first-ever combined mechanical heart pump and gene-edited pig kidney transplant surgery in a 54-year-old woman…
Biophysics: Testing how well biomarkers work
LMU researchers have developed a method to determine how reliably target proteins can be labeled using super-resolution fluorescence microscopy. Modern microscopy techniques make it possible to examine the inner workings…
