Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers Isolate Genes for Mosquito’s Sense of Smell

28.11.2001


New research is helping to unravel the machinery that allows a mosquito to sniff out its human quarry, which could lead to more and better ways of foiling the disease-spreading insects. A report published today in the online version of the Proceedings of the National Academy of Sciences describes four genes that appear to produce odor-sensing molecules in Africa’s Anopheles gambiae, a carrier of malaria, the number two killer in the developing world. Understanding how such genes operate could enable scientists to develop new compounds that will repel mosquitoes or lure them to poisons. Such chemicals are needed, senior author Laurence J. Zwiebel of Vanderbilt University explains, because "current levels of malaria and other insect-borne diseases suggest that we’re not controlling these insects very well."



Zwiebel and colleagues scanned the mosquito genome looking for genes similar to those that generate fruit fly odorant receptors, proteins that project from nerve cells and initiate a biochemical cascade when they encounter certain molecules in the air. The four candidates the team found were all active in the antennae and mouthparts of the mosquito, where its sense of smell resides. Significantly, one of the genes the team isolated was active only in females—the mosquito gender that bites—and its activity dropped off sharply 12 hours after a blood meal. Previous studies have found that a female’s sense of smell is dulled after feeding on human blood. Zwiebel says he and co-workers have now isolated a total of 30 possible receptors, and he expects to find anywhere from 60 to 100 in the end.

"Understanding the switch in the mosquito nose is just step one," he notes. Individual receptors generally bind to a range of molecules with varying strengths. A longer and more difficult task, he says, will be to figure out how a mosquito’s brain processes the signals that various receptors send. Controlling malaria will require an international effort, Zwiebel stresses, and "we hope that by identifying these sorts of genes… we’ll be able to help."

JR Minkel | Scientific American
Further information:
http://www.sciam.com/news/112701/1.html

More articles from Life Sciences:

nachricht Researchers identify potentially druggable mutant p53 proteins that promote cancer growth
09.12.2016 | Cold Spring Harbor Laboratory

nachricht Plant-based substance boosts eyelash growth
09.12.2016 | Fraunhofer-Institut für Angewandte Polymerforschung IAP

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Electron highway inside crystal

Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.

Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

09.12.2016 | Life Sciences

Scientists produce a new roadmap for guiding development & conservation in the Amazon

09.12.2016 | Ecology, The Environment and Conservation

Satellites, airport visibility readings shed light on troops' exposure to air pollution

09.12.2016 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>