Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Proteins, like people, act differently when crowded together

03.12.2010
People in a jetliner act and feel one way when crammed together like sardines in a can. But they have quite a different mindset when the middle seat is empty and they have more personal space.

Scientists are pursuing a remarkable parallel that exists among the proteins involved in health and disease inside living cells. The cover story in the current issue of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine, focuses on how the study of proteins crowded together inside cells is opening new doors to the prevention, diagnosis, and treatment of disease.

C&EN Senior Editor Celia Henry Arnaud notes that much of the scientific knowledge about proteins comes from research done in watered-down solutions, as if they had much of an airplane or cell to themselves. But cells are packed with proteins, which fill about 30 percent of a cell's volume. In order to understand proteins' actual role, scientists must study proteins under these jam-packed conditions.

The article describes how scientists are forging ahead with research that mimics the real-world conditions under which proteins function in cells. One discovery, for example, indicates that under crowded conditions, a protein involved in Lyme disease changes shape in a way that reveals a potential new target for diagnosing and treating the disease.

ARTICLE FOR IMMEDIATE RELEASE "Close Quarters"

This story is available at http://pubs.acs.org/cen/coverstory/88/8848cover.html

Michael Bernstein | EurekAlert!
Further information:
http://www.acs.org
http://pubs.acs.org/cen/coverstory/88/8848cover.html

More articles from Life Sciences:

nachricht More genes are active in high-performance maize
19.01.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht How plants see light
19.01.2018 | Albert-Ludwigs-Universität Freiburg im Breisgau

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Artificial agent designs quantum experiments

On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.

We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Let the good tubes roll

19.01.2018 | Materials Sciences

How cancer metastasis happens: Researchers reveal a key mechanism

19.01.2018 | Health and Medicine

Meteoritic stardust unlocks timing of supernova dust formation

19.01.2018 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>