When buying shoes it does not matter how good-looking the shoes might be if the size does not fit. This is similar with nanoparticles, which are made by the so-called emulsion-solvent evaporation process.
This process allows for the production of nanoparticles with high purity. Nevertheless they can still be improved: so far, their size distribution cannot be fully controlled. However, a defined size is of prime importance for future applications, whether it is for drug delivery or for intelligent coatings.
An interdisciplinary and international research collaboration at the Max Planck Institute for Polymer Research in Mainz was able to rule out coalescence as reason for the borad nanoparticle size distribution. Coalescence describes the tendency of colloidal droplets to melt together.
For the first time, Daniel Crespy, who is group leader in the department of Katharina Landfester, was able to prove that the coalescence between droplets during the process is not significantly responsible for the broad size distribution of the particles.“This study elucidates the mechanism of a common process used for the preparation of nanoparticles,“ says Daniel Crespy about his research results.
Stephan Imhof | Max-Planck-Institut
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