Professor Jian-Ren Shen is recognized for his pioneering research on clarifying the fundamental reaction mechanism that governs photosynthetic water splitting, a process with fundamental importance in understanding how oxygenic photosynthetic organisms, such as plants, use energy from sunlight, water, and CO2 to survive.
Structure of PS II dimer
“I first started research on photosynthetic proteins in the beginning of my doctorate project,” says Shen. “Our findings published in 2011 were based on x-ray diffraction experiments of large, high quality single crystal of so-called ‘photosystem II’ (PS II) at Japan’s SPring-8 synchrotron radiation facility at Harima. The ability to produce large sized, single crystals of PS II, an extremely large membrane-protein complex, was critical for determining the crystalline structure of this protein complex to a resolution of 1.9 Angstroms. These results are the culmination of 20 years of my life spent on the development and improvement of the process to produce such large crystals.”
Professor Shen’s initial research on photosynthesis was focused on clarifying the effects of air pollution on plants. The objectives of this research necessitated clarification of the fundamental mechanism underlying photosynthesis, which in turn required the production of a high quality crystal of PS II. “After many years of exhaustive experiments and uncountable failures, we eventually succeeded in producing large, ‘tofu-like’ single crystals of PS II with dimensions of 0.7 x 0.4 x 0.1 mm,” explains Shen. “This was a major breakthrough that led to the ultra-high resolution analysis of PS II.”
Recent reports on the crystallographic analysis of PS II can be traced back to the early 2000s but the results yielded only ‘fuzzy’ images because of imperfections in the samples. In contrast the 2011 findings by Shen and colleagues yielded unprecedented images of the core of the PS II protein, showing the existence of cubic-core of four manganese atoms, five oxygen atoms, and a calcium atom, which constitutes the heart of plant life (Science 2011, 334, 1630).
“This cubic structure of Mn4CaO5 acts as a catalyst for the water splitting reaction induced by sunlight,” explains Shen. “These results have many important practical applications including the possibility of synthesizing artificial catalyst to dissociate water into oxygen and hydrogen to produce electricity in fuel cells, for example.”
Indeed there is increasing interests in ‘artificial photosynthesis’ for the production of energy. But Professor Shen says that his group will focus on basic research on the reaction mechanism of PS II. “Our next goal is to clarify the so-called ‘intermediate structure’ of PS II,” says Shen. “To do so we require even higher resolution x-ray diffraction experiments at both space and time levels. We are planning to use the SACLA X-ray Free Electron Laser (XFEL) facility in SPring-8 to achieve this. This will enable us to look at the movement of atoms during photosynthesis.”
Professor Shen’s contributions to clarifying the mechanisms underlying photosynthesis have received many accolades including the ‘Breakthrough of the Year’ for 2011 by AAAS Science; the 2012 Asahi Prize; and the launch of the Okayama University Photosynthesis Research Center on 1 April 2013.Further information:
Journal information1. Yasufumi Umena (1), Keisuke Kawakami (2), Jian-Ren Shen (2) and Nobuo Kamiya (1), Crystal structure of oxygen-evolving photosystem II at a resolution of 1.9 Å; Nature 473, 55–61, (2011).
2 Division of Bioscience, Graduate School of Natural Science and Technology/Faculty of Science; Okayama University, Okayama 700-8530, Japan.
Researchers pave the way for ionotronic nanodevices
23.02.2017 | Aalto University
Microhotplates for a smart gas sensor
22.02.2017 | Toyohashi University of Technology
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
24.02.2017 | Life Sciences
24.02.2017 | Life Sciences
24.02.2017 | Trade Fair News