New Furin Inhibitors for Treatment of Infectious Diseases

Novel peptidomimetic furin inhibitors strongly inhibit the furin-dependent activation of several viral surface proteins and bacte-rial toxins. Therefore, these inhibitors are a promising new approach for the treatment of diseases, which are caused by furin-dependent infectious agents.
Such diseases are for example influenza, measles, mumps, yellow fever, canine distemper, anthrax, and diphtheria.

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