Treatment of Obesity
The invention consists in a method of inducing lipid oxidation or increasing insulin sensitivity through the administration of a ligand which binds to the IL-6 receptor and signals via a gp130/LIF (leukemia inhibitory factor) receptor heterodimer. The chimeric ligand has the potential to be a highly effective therapy for obesity. Through this new methodology for increasing lipid oxidation there is no induction of an inflammatory state, no high concentrations of cytokine need to be used and no autoantibodies will be generated. The invention is particularly useful in treating subjects suffering from symptoms caused by obesity, excessive appetite and overweight, as well as obesity-associated metabolic disorders such as hypertension, osteoarthritis, type II diabetes, increased blood pressure, stroke and heart disease.
Further Information: PDF
Patent- und Verwertungsagentur für die Wissenschaftlichen Einrichtungen in Schleswig-Holstein GmbH (PVA SH)
Phone: +49 (0)431/8009937
Contact
Dr. Alexandra Baumgartner
Media Contact
All latest news from the category: Technology Offerings
Newest articles
A universal framework for spatial biology
SpatialData is a freely accessible tool to unify and integrate data from different omics technologies accounting for spatial information, which can provide holistic insights into health and disease. Biological processes…
How complex biological processes arise
A $20 million grant from the U.S. National Science Foundation (NSF) will support the establishment and operation of the National Synthesis Center for Emergence in the Molecular and Cellular Sciences (NCEMS) at…
Airborne single-photon lidar system achieves high-resolution 3D imaging
Compact, low-power system opens doors for photon-efficient drone and satellite-based environmental monitoring and mapping. Researchers have developed a compact and lightweight single-photon airborne lidar system that can acquire high-resolution 3D…
