Monoclonale antibody: Mouse anti-human complement Factor H
Scientists at the Georg-August-University produced monoclonal antibodies which react with the polymorphic variant of human complement Factor H (FH-402(His), a marker for age-related macular degeneration. These peptide-specific antibodies specifically react with the polymorphic variants of human complement Factor H (either FH-402Y or FH-402H). Therefor they can be used for the screening of individuals at risk for developing AMD, as well as for the functional characterization of complement Factor H variants. AMD is the leading cause of blindness in the elderly. Because there is the chance to treat AMD with a new drug ( anti-VEGF-antibodies) nowadays this would increase the value of a new diagnostic screening assay.
Further Information: PDF
MBM ScienceBridge GmbH
Phone: (0551) 30724-151
Contact
Dr. Jens-Peter Horst
Media Contact
All latest news from the category: Technology Offerings
Newest articles
Airborne single-photon lidar system achieves high-resolution 3D imaging
Compact, low-power system opens doors for photon-efficient drone and satellite-based environmental monitoring and mapping. Researchers have developed a compact and lightweight single-photon airborne lidar system that can acquire high-resolution 3D…
Simplified diagnosis of rare eye diseases
Uveitis experts provide an overview of an underestimated imaging technique. Uveitis is a rare inflammatory eye disease. Posterior and panuveitis in particular are associated with a poor prognosis and a…
Targeted use of enfortumab vedotin for the treatment of advanced urothelial carcinoma
New study identifies NECTIN4 amplification as a promising biomarker – Under the leadership of PD Dr. Niklas Klümper, Assistant Physician at the Department of Urology at the University Hospital Bonn…
