Use of ADAM 12 for diagnosis and therapy of preeclampsia

Preeclampsia is a disorder affecting

about 5% of pregnant women. It becomes manifest in the last trimester of pregnancy and is characterized by high blood pressure, protein in the urine, and, sometimes, edema of the face and hands. When left untreated, preeclampsia can lead to severe problems, endangering both mother and fetus. High blood pressure constricts the blood vessels in the uterus that supply the fetus with oxygen and nutrients. Fetal growth is retarded. Preeclampsia can increase the risk of:  placental abruption  kidney failure  cerebral hemorrhage  intravascular coagulation  lung edema  circulatory collapse

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DKFZ (German Cancer Research Center, Deutsches Krebsforschungszentrum)
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Dr. Ruth Herzog