Marking a significant bench to bedside research milestone in Singapore, the Institute of Bioengineering and Nanotechnology (IBN), the world's first bioengineering and nanotechnology research institute, and the National University Hospital (NUH) launched the IBN iCare and the NUH Eye Centre @ Biopolis at an official opening ceremony officiated by the Senior Minister of State for Trade and Industry and Education, S. Iswaran, at the Biopolis on Nov. 3, 2009.
Collaborations between researchers and clinicians are critical to speed up the translation of basic scientific discoveries into clinical applications, and develop new medical products and treatments. IBN iCare is the first research laboratory in Singapore to focus on the development of cutting-edge nanomaterials for ocular therapy.
The NUH Eye Centre @ Biopolis will provide a clinical research environment that facilitates the development of new materials and techniques for ophthalmology practice. IBN's nanostructured ocular materials will undergo clinical trials at the NUH Eye Centre prior to commercial applications.
Since 2003, IBN has been revolutionizing medical treatment with sophisticated biomaterials and systems for delivering therapeutics to diseased cells and organs. This key research thrust at IBN has led to the synthesis of a novel drug-loaded contact lens that can deliver medication more effectively than eye drops for the treatment of eye diseases such as glaucoma. The latest ocular research invention created by IBN is the world's first photochromic contact lens that will darken upon exposure to sunlight to protect the eyes against harmful ultraviolet radiation and glare. The lenses will conveniently adapt to changes in light and provide optimal indoor and outdoor vision.
"IBN's mission is to conduct strategic research that addresses important biomedical problems through novel technology platforms that present major commercial potential. The launch of IBN iCare and our collaboration with NUH symbolize our commitment towards establishing Singapore as an international, world class biomedical hub. By bridging the gap from bench to bedside, we are well positioned to facilitate the commercialization of our research innovations," said Professor Jackie Y. Ying, IBN Founding Executive Director.
Recognizing the commercial potential of IBN's ocular biomaterials, Exploit Technologies Pte Ltd (ETPL), the strategic marketing and commercialization arm of the Agency for Science, Technology and Research (A*STAR), provided a S$5 million Flagship Fund to set up IBN iCare. IBN iCare will accelerate the translation of strategic research in vision care to viable medical products and treatments. Its mission is to incubate start-up companies in vision care, and attract more global partners to Singapore to create a major commercial impact on myopia and vision impairment treatment.
Boon Swan Foo, Executive Chairman of Exploit Technologies, said, "Exploit Technologies is pleased to have partnered IBN and NUH in building this tripartite commercialisation effort. The bringing together of clinicians with scientists and commercial people to this juncture is due to the unrelenting effort of the key players, including Dr. Muhammad Tani, Professor Jackie Ying and Associate Professor Paul Chew who have worked hard to overcome obstacles along the way. Our team started to work on the project since 2005; it was a time when the market was not ready for adoption of the drug eluting nanoporous contact lens technology. We ploughed the market, evolved our marketing strategies, and essentially created a market when there was none. Through our efforts, the technology was licensed to a MNC in 2006, with a contract value of more than S$100 million. To further exploit the technology's commercial potential, we held discussions with clinicians and industry players to find out other potential applications; and the idea of the NUH Eye Centre was born in 2007. To ensure the success of this meaningful project, Exploit Technologies launched a Flagship project, coupled with an S$5 million funding, to help set up IBN iCare and NUH Eye Centre @ Biopolis.
"Today, we see the fruits of our labour. I am delighted that big players like SAF and Carl Zeiss are partnering us in the effort to take R&D from the lab to market. Additionally, two Singapore-based companies have already expressed interest to license IBN's photochromic contact lens. I am encouraged that diverse teams with proper leadership and good technologies can lead to a successful start of a great future ahead."
In addition to research, the NUH Eye Centre @ Biopolis will also provide a wide range of eye care services, LASIK and refractive surgery for patients. The patient-centric centre is designed with the patient's interest and safety in mind. For example, to improve the patient's experience, the configuration of the centre optimises the patient flow by guiding them through the various eye-check stations. The LASIK operating suite also complies with stringent guidelines to enhance patients' safety. Another interesting feature is the see-through glass that allows the patients' family members to observe the LASIK procedure. Innovative treatment of vision correction using IBN's biomaterials will also be widely offered through the NUH Eye Centre @ Biopolis.
Joe Sim, NUH Chief Executive Officer, said, "Having one of our eye facilities located in the Biopolis means we are right within the research hub. This will facilitate greater opportunities for research collaboration which is aligned with our focus as an academic medical centre. Our partnership with IBN will allow us to work closely with researchers on projects that will potentially translate to better care to benefit our patients and Singaporeans."
The close proximity of the eye clinic to IBN iCare at the Biopolis will strengthen the partnership between NUHS ophthalmologists and IBN researchers to better meet the healthcare needs of the patients. Besides eye care, IBN scientists can also work closely with clinicians at NUH to advance collaborations in IBN's four research areas: Drug and Gene Delivery, Cell and Tissue Engineering, Biosensors and Biodevices, Pharmaceuticals Synthesis and Nanobiotechnology.
The initiative by IBN iCare and NUH Eye Centre @ Biopolis will also expedite the route to commercialization by bridging the gap from bench to industry. IBN is working with Carl Zeiss, a global leader in the optical industries, on the development of technologies and treatments associated with IBN's innovative ocular biomaterials. The Singapore Armed Forces (SAF) Medical Corps is also partnering with IBN and NUH in research and training for vision correction technology to address the problems of myopia and ocular trauma in SAF operations.
Study tracks inner workings of the brain with new biosensor
16.08.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn
Foods of the future
15.08.2018 | Georg-August-Universität Göttingen
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.
Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...
Scientists have discovered that the electrical resistance of a copper-oxide compound depends on the magnetic field in a very unusual way -- a finding that could help direct the search for materials that can perfectly conduct electricity at room temperatur
What happens when really powerful magnets--capable of producing magnetic fields nearly two million times stronger than Earth's--are applied to materials that...
08.08.2018 | Event News
27.07.2018 | Event News
25.07.2018 | Event News
16.08.2018 | Life Sciences
16.08.2018 | Earth Sciences
16.08.2018 | Life Sciences