You might want to toss those iron-fortified vitamins, because absent a diagnosed deficiency too much of a good thing can be bad.
Dietary iron imbalances either way spell trouble for healthy cells, triggering a chain of cellular events in the brain that increases the odds of developing Parkinsons disease, a degenerative condition affecting movement and balance in more than 1 million Americans each year. But excessive iron levels are worse -- much worse.
The findings from a study by Florida State University scientist Cathy Levenson are described in "The Role of Dietary Iron Restrictions in a Mouse Model of Parkinsons Disease" and will appear in an upcoming edition of Experimental Neurology. Levenson is an associate professor of nutrition, food and exercise sciences in FSUs College of Human Sciences and a faculty member in both the Program in Neuroscience and graduate program in molecular biophysics. "We define our work here at the cellular level," said Levenson from her laboratory at FSUs Biomedical Research Facility. "Our primary research objective is to better understand how trace metal imbalances, which are associated with neuropsychiatric and neurodegenerative diseases, affect the molecular mechanisms that regulate gene expression."
Cathy Levenson | EurekAlert!
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Bioinspired nanoscale drug delivery method developed by WSU, PNNL researchers
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The scientific and political community alike stress the importance of German Antarctic research
Joint Press Release from the BMBF and AWI
The Antarctic is a frigid continent south of the Antarctic Circle, where researchers are the only inhabitants. Despite the hostile conditions, here the Alfred...
World first experiments on sensor that may revolutionise everything from medical devices to unmanned vehicles
The new sensor - capable of detecting vibrations of living cells - may revolutionise everything from medical devices to unmanned vehicles.
Dead and alive at the same time? Researchers at the Max Planck Institute of Quantum Optics have implemented Erwin Schrödinger’s paradoxical gedanken experiment employing an entangled atom-light state.
In 1935 Erwin Schrödinger formulated a thought experiment designed to capture the paradoxical nature of quantum physics. The crucial element of this gedanken...
Cellulose obtained from wood has amazing material properties. Empa researchers are now equipping the biodegradable material with additional functionalities to produce implants for cartilage diseases using 3D printing.
It all starts with an ear. Empa researcher Michael Hausmann removes the object shaped like a human ear from the 3D printer and explains:
The phenomenon of so-called superlubricity is known, but so far the explanation at the atomic level has been missing: for example, how does extremely low friction occur in bearings? Researchers from the Fraunhofer Institutes IWM and IWS jointly deciphered a universal mechanism of superlubricity for certain diamond-like carbon layers in combination with organic lubricants. Based on this knowledge, it is now possible to formulate design rules for supra lubricating layer-lubricant combinations. The results are presented in an article in Nature Communications, volume 10.
One of the most important prerequisites for sustainable and environmentally friendly mobility is minimizing friction. Research and industry have been dedicated...
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