Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Antibiotics within 4 hours of arrival at hospital better for pneumonia patients

23.03.2004


Giving older patients antibiotics within four hours of their arrival at a hospital for treatment of pneumonia reduces the length of hospital stay, and may reduce the chances of dying, according to an article in the March 22 issue of The Archives of Internal Medicine, one of the JAMA/Archives journals.



According to the article, pneumonia is the second leading reason for hospitalization among Medicare beneficiaries, accounting for more than 600,000 Medicare hospitalizations yearly, and is the fifth leading cause of death among Americans older than 65 years. Timely administration of antibiotics to hospitalized patients with pneumonia has been associated with improved survival, the article states. Guidelines recommend antibiotic treatment within eight hours of arrival at a hospital.

Peter M. Houck, M.D., from the Centers for Medicare & Medicaid Services, Seattle, and colleagues investigated whether administration of antibiotics within less than eight hours of arrival at the hospital was associated with significant improvements in hospitalized patients with pneumonia who had not been treated prior to arriving at the hospital.


The researchers examined medical records from a national random sample of 18,209 Medicare patients older than 65 years who were hospitalized with pneumonia from July 1998 through March 1999.

Among the 13,771 (75.6 percent) of patients who did not receive any treatment prior to their arrival at a hospital, antibiotic administration within four hours of arrival was associated with reduced death in the hospital (6.8 percent vs. 7.4 percent), reduced likelihood of dying within 30 days of admission to the hospital (11.6 percent vs. 12.7 percent) and reduced likelihood that the length of stay (LOS) at the hospital exceeded 5 days (42.1 percent vs. 45.1 percent). The average length of stay was an average of about half a day shorter for patients who received antibiotics within four hours of arriving at the hospital. The researchers also found that 60.9 percent of all patients received antibiotics within four hours of arriving at a hospital.

"The results of this study suggest that initial administration of antibiotics within four hours of arrival at the hospital is associated with reduced mortality among those patients who have not received antibiotics as outpatients and reduced hospital LOS among all patients," write the authors. "While most Medicare inpatients with pneumonia already receive antibiotics within that time, a substantial proportion do not. Given the growing size of the Medicare population, any additional improvement in administration timing could prevent a substantial number of deaths each year and preserve health care resources."


To contact Peter M. Houck, M.D., call the Centers for Medicare & Medicaid Services Office of Public Affairs at 202-690-6145.

(Arch Intern Med. 2004;164:637-644. Available post-embargo at archinternmed.com)

For more information, contact JAMA/Archives Media Relations at 312-464-JAMA (5262) or e-mail mediarelations@jama-archives.org .

| EurekAlert!
Further information:
http://www.jama.com/

More articles from Health and Medicine:

nachricht Photoactive bacteria bait may help in fight against MRSA infections
12.10.2018 | Purdue University

nachricht 15 emerging technologies that could reduce global catastrophic biological risks
10.10.2018 | Johns Hopkins Center for Health Security

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Storage & Transport of highly volatile Gases made safer & cheaper by the use of “Kinetic Trapping"

Augsburg chemists present a new technology for compressing, storing and transporting highly volatile gases in porous frameworks/New prospects for gas-powered vehicles

Storage of highly volatile gases has always been a major technological challenge, not least for use in the automotive sector, for, for example, methane or...

Im Focus: Disrupting crystalline order to restore superfluidity

When we put water in a freezer, water molecules crystallize and form ice. This change from one phase of matter to another is called a phase transition. While this transition, and countless others that occur in nature, typically takes place at the same fixed conditions, such as the freezing point, one can ask how it can be influenced in a controlled way.

We are all familiar with such control of the freezing transition, as it is an essential ingredient in the art of making a sorbet or a slushy. To make a cold...

Im Focus: Micro energy harvesters for the Internet of Things

Fraunhofer IWS Dresden scientists print electronic layers with polymer ink

Thin organic layers provide machines and equipment with new functions. They enable, for example, tiny energy recuperators. In future, these will be installed...

Im Focus: Dynamik einzelner Proteine

Neue Messmethode erlaubt es Forschenden, die Bewegung von Molekülen lange und genau zu verfolgen

Das Zusammenspiel aus Struktur und Dynamik bestimmt die Funktion von Proteinen, den molekularen Werkzeugen der Zelle. Durch Fortschritte in der...

Im Focus: Dynamics of individual proteins

New measurement method allows researchers to precisely follow the movement of individual molecules over long periods of time

The function of proteins – the molecular tools of the cell – is governed by the interplay of their structure and dynamics. Advances in electron microscopy have...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Berlin5GWeek: Private industrial networks and temporary 5G connectivity islands

16.10.2018 | Event News

5th International Conference on Cellular Materials (CellMAT), Scientific Programme online

02.10.2018 | Event News

Major Project: The New Silk Road

01.10.2018 | Event News

 
Latest News

Unravelling the genetics of fungal fratricide

16.10.2018 | Life Sciences

Blue phosphorus -- mapped and measured for the first time

16.10.2018 | Physics and Astronomy

Berlin5GWeek: Private industrial networks and temporary 5G connectivity islands

16.10.2018 | Event News

VideoLinks
Science & Research
Overview of more VideoLinks >>>