Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Single Crystals as Reaction Vessels

02.09.2008
In a crystal, but like in solution: chemical reactions in the pores of single crystals

Japanese researchers from the University of Tokyo have made a complex that crystallizes as a porous solid.

Common reagents, even bulky ones, can easily diffuse into these pores and are sufficiently mobile to react with embedded substrates. As they report in the journal Angewandte Chemie, the pores act as a sort of crystalline molecular test tube.

The reaction products can then be directly examined by X-ray crystallographic methods.

Only single crystals can be examined by X-ray crystallography. The crystal’s diffraction of X-rays can be used to determine its structure. Liquids are not so easy to analyze. In solid-state reactions, this technique is limited to cases in which the structural changes are very small. Bulky reactants cannot even get into an ordinary tightly packed crystal, and crystals often decompose in the course of the reaction.

A team led by Makoto Fujita has developed a complex of zinc ions and aromatic ring systems that crystallizes into a robust network with large pores. The compound is constructed so that reactive groups of atoms, such as amino groups, protrude into the pores. Dipping the crystals into a solution containing common reactants brings these into contact with the embedded reaction partners. Even bulky molecules can get into the large pores. The researchers were thus able to react the amino groups with acetic anhydride or aniline. The reactivity of the reagents used and the course of the reaction are no different than if the reactants encountered each other freely in solution. The crystal changed color little by little, but remained intact in crystalline form despite the reaction.

Because the final product of the reaction is still in the form of a single crystal, the course of the reaction can be followed by X-ray crystallographic methods. Labile reaction products and intermediates can thus be produced and detected in situ. The chemical reactions within the pores can also be used to modify the walls of the pores as needed. For example, they can be equipped with free acid groups.

Author: Makoto Fujita, University of Tokyo (Japan), http://fujitalab.t.u-tokyo.ac.jp/members_e/mfujita/

Title: Single-Crystalline Molecular Flasks: Chemical Transformation with Bulky Reagents in the Pores of Porous Coordination Networks

Angewandte Chemie International Edition, doi: 10.1002/anie.200802545

Makoto Fujita | Angewandte Chemie
Further information:
http://pressroom.angewandte.org
http://fujitalab.t.u-tokyo.ac.jp/members_e/mfujita/

More articles from Life Sciences:

nachricht Turning carbon dioxide into liquid fuel
06.08.2020 | DOE/Argonne National Laboratory

nachricht Tellurium makes the difference
06.08.2020 | Friedrich-Schiller-Universität Jena

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: ScanCut project completed: laser cutting enables more intricate plug connector designs

Scientists at the Fraunhofer Institute for Laser Technology ILT have come up with a striking new addition to contact stamping technologies in the ERDF research project ScanCut. In collaboration with industry partners from North Rhine-Westphalia, the Aachen-based team of researchers developed a hybrid manufacturing process for the laser cutting of thin-walled metal strips. This new process makes it possible to fabricate even the tiniest details of contact parts in an eco-friendly, high-precision and efficient manner.

Plug connectors are tiny and, at first glance, unremarkable – yet modern vehicles would be unable to function without them. Several thousand plug connectors...

Im Focus: New Strategy Against Osteoporosis

An international research team has found a new approach that may be able to reduce bone loss in osteoporosis and maintain bone health.

Osteoporosis is the most common age-related bone disease which affects hundreds of millions of individuals worldwide. It is estimated that one in three women...

Im Focus: AI & single-cell genomics

New software predicts cell fate

Traditional single-cell sequencing methods help to reveal insights about cellular differences and functions - but they do this with static snapshots only...

Im Focus: TU Graz Researchers synthesize nanoparticles tailored for special applications

“Core-shell” clusters pave the way for new efficient nanomaterials that make catalysts, magnetic and laser sensors or measuring devices for detecting electromagnetic radiation more efficient.

Whether in innovative high-tech materials, more powerful computer chips, pharmaceuticals or in the field of renewable energies, nanoparticles – smallest...

Im Focus: Tailored light inspired by nature

An international research team with Prof. Cornelia Denz from the Institute of Applied Physics at the University of Münster develop for the first time light fields using caustics that do not change during propagation. With the new method, the physicists cleverly exploit light structures that can be seen in rainbows or when light is transmitted through drinking glasses.

Modern applications as high resolution microsopy or micro- or nanoscale material processing require customized laser beams that do not change during...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“Conference on Laser Polishing – LaP 2020”: The final touches for surfaces

23.07.2020 | Event News

Conference radar for cybersecurity

21.07.2020 | Event News

Contact Tracing Apps against COVID-19: German National Academy Leopoldina hosts international virtual panel discussion

07.07.2020 | Event News

 
Latest News

Rare Earth Elements in Norwegian Fjords?

06.08.2020 | Earth Sciences

Anode material for safe batteries with a long cycle life

06.08.2020 | Power and Electrical Engineering

Turning carbon dioxide into liquid fuel

06.08.2020 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>