Nitric oxide, normally toxic at high concentrations, is now known to be involved in a number of functions within the nervous system of many animals. New research being presented today at the Society for Experimental Biology conference reveals for the first time that nitric oxide is also present within the neurosecretory system of fish and may help them cope with changes in environmental salinity.
Within the mammalian nervous system it was thought that nerve cells communicated exclusively using `traditional` neurotransmitters - small peptide molecules which travel between nerve cells binding to their surface and causing them to become electrically excited. It is now believed that a new class of transmitter exists - nitric oxide (NO). As a gas, NO is able to penetrate the cell and act directly within it, modulating its activity and allowing a rapid reaction to environmental change. This transmitter has been implicated in a variety of nervous functions from olfaction -the sense of smell - to hormone release.
The presence and activity of nitric oxide has, in the last 10 years, been demonstrated in almost every species of animal, says Dr Carla Cioni of `La Sapienza` University, Rome. At the conference in Swansea, Dr Cioni will show that NO may play a role within the neurosecretory system of fish. Fish possess two neurosecretory systems - essentially nerve cells which are able to release hormones - in the brain and, strangely, the tail. The system in the tail is known as the urophysis and produces urotensins. These proteins are released into the blood and cause circulatory changes which may help the fish to cope with changes in salinity.
Jenny Gimpel | alphagalileo
Lethal combination: Drug cocktail turns off the juice to cancer cells
12.12.2018 | Universität Basel
Smelling the forest – not the trees
12.12.2018 | Universität Konstanz
A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.
The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...
A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.
Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...
Over the last decade, there has been much excitement about the discovery, recognised by the Nobel Prize in Physics only two years ago, that there are two types...
What if a sensor sensing a thing could be part of the thing itself? Rice University engineers believe they have a two-dimensional solution to do just that.
Rice engineers led by materials scientists Pulickel Ajayan and Jun Lou have developed a method to make atom-flat sensors that seamlessly integrate with devices...
Scientists at the University of Stuttgart and the Karlsruhe Institute of Technology (KIT) succeed in important further development on the way to quantum Computers.
Quantum computers one day should be able to solve certain computing problems much faster than a classical computer. One of the most promising approaches is...
12.12.2018 | Event News
10.12.2018 | Event News
06.12.2018 | Event News
12.12.2018 | Health and Medicine
12.12.2018 | Physics and Astronomy
12.12.2018 | Health and Medicine