Scientists in the Conway Institute of Biomolecular & Biomedical Research have restored the sight of blind zebrafish whose eyes failed to develop due to a genetic mutation. The findings, published this week in Developmental Biology, are exciting first steps on a long road to understanding eye diseases in humans.
Dr. Breandan Kennedy and his colleagues at the University of Washington, Seattle and the Hubrecht Laboratory in Utrecht, Netherlands first identified a family of eyeless fish. They then discovered the gene that controls initial development of eye tissue (retinal homeobox 3 or rx3) and that mutations in this gene resulted in the eyeless fish.
When Dr. Kennedy and his research team introduced a normal copy of the rx3 gene into fish embryos that had inherited the mutated version of the gene, they discovered that this treatment restored normal eye development. Recent studies from researchers in the Unites States have shown that mutations in the human form of this gene cause anophthalmia, a disease in which eyes also fail to form.
Nanocages in the lab and in the computer: how DNA-based dendrimers transport nanoparticles
19.10.2018 | University of Vienna
Less animal experiments on the horizon: Multi-organ chip awarded
19.10.2018 | Fraunhofer-Institut für Werkstoff- und Strahltechnik IWS
Scientists at the Max Planck Institute for Polymer Research (MPI-P) in Mainz (Germany) together with scientists from Dresden, Leipzig, Sofia (Bulgaria) and Madrid (Spain) have now developed and characterized a novel, metal-organic material which displays electrical properties mimicking those of highly crystalline silicon. The material which can easily be fabricated at room temperature could serve as a replacement for expensive conventional inorganic materials used in optoelectronics.
Silicon, a so called semiconductor, is currently widely employed for the development of components such as solar cells, LEDs or computer chips. High purity...
Augsburg chemists present a new technology for compressing, storing and transporting highly volatile gases in porous frameworks/New prospects for gas-powered vehicles
Storage of highly volatile gases has always been a major technological challenge, not least for use in the automotive sector, for, for example, methane or...
When we put water in a freezer, water molecules crystallize and form ice. This change from one phase of matter to another is called a phase transition. While this transition, and countless others that occur in nature, typically takes place at the same fixed conditions, such as the freezing point, one can ask how it can be influenced in a controlled way.
We are all familiar with such control of the freezing transition, as it is an essential ingredient in the art of making a sorbet or a slushy. To make a cold...
Thin organic layers provide machines and equipment with new functions. They enable, for example, tiny energy recuperators. In future, these will be installed...
Das Zusammenspiel aus Struktur und Dynamik bestimmt die Funktion von Proteinen, den molekularen Werkzeugen der Zelle. Durch Fortschritte in der...
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