A Rutgers-led team has produced the first ever measurement of the "heat of life" – the energies involved in DNA replication and synthesis. The researchers findings have opened the door to a better understanding of the origins of replication errors that can result in genetic mutations and serious illness. This is crucial knowledge for the development of medical diagnostics and treatments of genetic disorders.
"Our measurements represent the first direct determination of the energies and their transformations in this most fundamental process in biological chemistry," said principal investigator Kenneth J. Breslauer, Linus C. Pauling Professor, and dean and director of the Division of Life Sciences, Rutgers, The State University of New Jersey.
Breslauer explained that the measurements can be used to construct a virtual landscape that traces the precise energy differences between correct and incorrect DNA synthesis. The differential energy signatures signal the presence of DNA damage, potentially repairable by protein systems inside the cell or specifically designed drugs administered from the outside, or both.
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15.11.2018 | Jacobs University Bremen gGmbH
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly
The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...
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15.11.2018 | Life Sciences
15.11.2018 | Life Sciences