Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Phage therapy could remove foodborne disease from livestock

19.05.2003


A bacteria-killing virus found in the feces of some sheep could help remove the dangerous foodborne bacteria Escherichia coli O157:H7 from livestock. Researchers from Evergreen State College in Olympia, Washington present their research today at the 103rd General Meeting of the American Society for Microbiology.



"Here we report a promising new natural way of reducing pathogen concentrations in livestock. This takes advantage of bacteriophages – bacteria-killing viruses, harmless to humans and other animals, which have been used extensively as antibiotics in Eastern Europe and the former Soviet Union for over 50 years," says Michael Dyen, one of the study researchers.

Dyen and his colleagues report on a new bacteriophage (CEV1) that they isolated from the feces of sheep naturally resistant to gut colonization by E. coli O157:H7. Preliminary trials of CEV1 in the lab have shown that it can be produced easily and can efficiently infect and kill the bacteria under proper conditions. In model systems reflecting the cow/sheep gut, CEV1 completely eliminated the bacteria in 11 days.


"CEV1 and other carefully-selected phages against E. coli O157:H7 could be used to develop an effective management strategy to eradicate this pathogen from livestock," says Dyen.

Outbreaks of Escherichia coli O157:H7 have been linked to the consumption of hamburger meat, alfalfa sprouts, unpasteurized fruit juice, and even drinking water; more than 75% of the cases can be directly traced to contamination from carrier ruminants. The most recent data suggest that about 28% of the cattle presented for slaughter in the US harbour O157:H7, and similar numbers have been reported in Canada and Europe. The livestock show no signs of illness and the levels are generally low, making contaminated animals hard to identify. Current prevention methodologies have centered on reducing meat contamination in the slaughterhouse and testing all products for human consumption as they leave.

"At present, there are few therapeutic treatments for victims of this potentially deadly infectious agent except supportive therapy to manage the complications of cellular damage," says Dyen. "Our work focuses on removing O157:H7 from the food chain."


###
This release is a summary of a presentation from the 103rd General Meeting of the American Society for Microbiology, May 18-22, 2003, in Washington, DC. Additional information on these and other presentations at the 103rd ASM General Meeting can be found online at http://www.asm.org/Media/index.asp?bid=17053 or by contacting Jim Sliwa (jsliwa@asmusa.org) in the ASM Office of Communications. The phone number for the General Meeting Press Room is (202) 249-4064 and will be active from 12:00 noon EDT, May 18 until 12:00 noon EDT, May 22.


Jim Sliwa | EurekAlert!
Further information:
http://www.asmusa.org/

More articles from Life Sciences:

nachricht New candidate for raw material synthesis through gene transfer
02.07.2020 | Karlsruher Institut für Technologie (KIT)

nachricht Marine alga from the Kiel Fjord discovered as a remedy against infections and skin cancer
02.07.2020 | Helmholtz Centre for Ocean Research Kiel (GEOMAR)

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: The lightest electromagnetic shielding material in the world

Empa researchers have succeeded in applying aerogels to microelectronics: Aerogels based on cellulose nanofibers can effectively shield electromagnetic radiation over a wide frequency range – and they are unrivalled in terms of weight.

Electric motors and electronic devices generate electromagnetic fields that sometimes have to be shielded in order not to affect neighboring electronic...

Im Focus: Gentle wall contact – the right scenario for a fusion power plant

Quasi-continuous power exhaust developed as a wall-friendly method on ASDEX Upgrade

A promising operating mode for the plasma of a future power plant has been developed at the ASDEX Upgrade fusion device at Max Planck Institute for Plasma...

Im Focus: ILA Goes Digital – Automation & Production Technology for Adaptable Aircraft Production

Live event – July 1, 2020 - 11:00 to 11:45 (CET)
"Automation in Aerospace Industry @ Fraunhofer IFAM"

The Fraunhofer Institute for Manufacturing Technology and Advanced Materials IFAM l Stade is presenting its forward-looking R&D portfolio for the first time at...

Im Focus: AI monitoring of laser welding processes - X-ray vision and eavesdropping ensure quality

With an X-ray experiment at the European Synchrotron ESRF in Grenoble (France), Empa researchers were able to demonstrate how well their real-time acoustic monitoring of laser weld seams works. With almost 90 percent reliability, they detected the formation of unwanted pores that impair the quality of weld seams. Thanks to a special evaluation method based on artificial intelligence (AI), the detection process is completed in just 70 milliseconds.

Laser welding is a process suitable for joining metals and thermoplastics. It has become particularly well established in highly automated production, for...

Im Focus: A structural light switch for magnetism

A research team from the Max Planck Institute for the Structure of Dynamics (MPSD) and the University of Oxford has managed to drive a prototypical antiferromagnet into a new magnetic state using terahertz frequency light. Their groundbreaking method produced an effect orders of magnitude larger than previously achieved, and on ultrafast time scales. The team’s work has just been published in Nature Physics.

Magnetic materials have been a mainstay in computing technology due to their ability to permanently store information in their magnetic state. Current...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

International conference QuApps shows status quo of quantum technology

02.07.2020 | Event News

Dresden Nexus Conference 2020: Same Time, Virtual Format, Registration Opened

19.05.2020 | Event News

Aachen Machine Tool Colloquium AWK'21 will take place on June 10 and 11, 2021

07.04.2020 | Event News

 
Latest News

The lightest electromagnetic shielding material in the world

02.07.2020 | Materials Sciences

Spintronics: Faster data processing through ultrashort electric pulses

02.07.2020 | Information Technology

International conference QuApps shows status quo of quantum technology

02.07.2020 | Event News

VideoLinks
Science & Research
Overview of more VideoLinks >>>