Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Europe-wide investment in lipid research will help tackle disease

18.06.2008
Leading scientists today called for Europe to invest more funds into the study of lipids – the 'fatty' molecules that play a crucial role in the function of human cells and which are implicated in a range of diseases from obesity and diabetes to Alzheimer's.

Common lipids such as cholesterol are known to play an important part in the normal functioning of cells and tissues, but human cells contain thousands of different lipids which are also vital for functions that include storing energy, maintaining the structure of the cell and sending biochemical signals. Scientists are discovering that if the biochemical pathways that regulate the metabolism and transport of these lipids become disturbed, this can result in disease.

A report* published today by the European Science Foundation (ESF) urges greater cooperation among researchers and more investment in the field of 'lipidomics' – the term given to the identification and analysis of the full complement of lipids in cells, tissues and body fluids, together with associated molecular structures such as enzymes and genes. The document is the output of a science policy activity led by the European Medical Research Councils (EMRC), the medical section within ESF.

The ESF science policy briefing document, drawn up by an international panel of experts led by Professor Gerrit van Meer of Utrecht University in The Netherlands and Professor Friedrich Spener of the University of Graz in Austria, says that the study of lipids has been largely neglected because until recently technology did not exist to analyse this complex class of molecules comprehensively. However, the application of an analytical technique called mass spectrometry now allows large numbers of lipids to be analysed rapidly. "This remarkable technological breakthrough will make it possible to better understand the cellular machineries that are responsible for producing and storing energy in cells, for the transport across and between cell membranes and for the signalling in and out of cells to name but a few examples," the report states.

... more about:
»Database »Disease »Lipid

A concerted research effort in lipidomics would help shed light on conditions ranging from obesity and heart disease to cancer and Alzheimer's, the report says, while pointing out that the number of European researchers with expertise in lipidomics is low and that increased funding is needed to help Europe to catch up with the level of research in countries such as Japan and the US.

The science policy briefing makes several key recommendations that would boost lipidomics research in Europe:

Investment in research programmes aimed at training biomedical scientists in lipid-related fields

Investment in further development of technologies for studying lipids, while establishing and maintaining strong links between technology developers and researchers

Development of a strong, coordinated and interdisciplinary research effort across Europe to understand lipid function and the roles of lipids in health and disease

Integration of European lipid databases and the facilitation of their communication with other databases worldwide. This would allow the 'holistic' interpretation of lipid data and provide a greater understanding of the role of lipids in health and disease.

Professor van Meer said, "Lipidomics not only involves the study of lipids, but it also involves enzymes, transporters, genes, proteins, and their biophysics. The challenge is to unite all these different datasets and bring them together with disease pathology in one concentrated database." Such an approach would provide invaluable new insights into diagnosing, monitoring and even curing disease, Professor van Meer added.

Professor Gerrit van Meer | EurekAlert!
Further information:
http://www.uu.nl

Further reports about: Database Disease Lipid

More articles from Life Sciences:

nachricht Identifying the blind spots of soil biodiversity
04.08.2020 | Deutsches Zentrum für integrative Biodiversitätsforschung (iDiv) Halle-Jena-Leipzig

nachricht AI & single-cell genomics
04.08.2020 | Helmholtz Zentrum München - German Research Center for Environmental Health

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: AI & single-cell genomics

New software predicts cell fate

Traditional single-cell sequencing methods help to reveal insights about cellular differences and functions - but they do this with static snapshots only...

Im Focus: TU Graz Researchers synthesize nanoparticles tailored for special applications

“Core-shell” clusters pave the way for new efficient nanomaterials that make catalysts, magnetic and laser sensors or measuring devices for detecting electromagnetic radiation more efficient.

Whether in innovative high-tech materials, more powerful computer chips, pharmaceuticals or in the field of renewable energies, nanoparticles – smallest...

Im Focus: Tailored light inspired by nature

An international research team with Prof. Cornelia Denz from the Institute of Applied Physics at the University of Münster develop for the first time light fields using caustics that do not change during propagation. With the new method, the physicists cleverly exploit light structures that can be seen in rainbows or when light is transmitted through drinking glasses.

Modern applications as high resolution microsopy or micro- or nanoscale material processing require customized laser beams that do not change during...

Im Focus: NYUAD astrophysicist investigates the possibility of life below the surface of Mars

  • A rover expected to explore below the surface of Mars in 2022 has the potential to provide more insights
  • The findings published in Scientific Reports, Springer Nature suggests the presence of traces of water on Mars, raising the question of the possibility of a life-supporting environment

Although no life has been detected on the Martian surface, a new study from astrophysicist and research scientist at the Center for Space Science at NYU Abu...

Im Focus: Manipulating non-magnetic atoms in a chromium halide enables tuning of magnetic properties

New approach creates synthetic layered magnets with unprecedented level of control over their magnetic properties

The magnetic properties of a chromium halide can be tuned by manipulating the non-magnetic atoms in the material, a team, led by Boston College researchers,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“Conference on Laser Polishing – LaP 2020”: The final touches for surfaces

23.07.2020 | Event News

Conference radar for cybersecurity

21.07.2020 | Event News

Contact Tracing Apps against COVID-19: German National Academy Leopoldina hosts international virtual panel discussion

07.07.2020 | Event News

 
Latest News

First radio detection of an extrasolar planetary system around a main-sequence star

04.08.2020 | Physics and Astronomy

The art of making tiny holes

04.08.2020 | Physics and Astronomy

Early Mars was covered in ice sheets, not flowing rivers

04.08.2020 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>