Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Biological physics creates diagnostics of the future

17.12.2007
Chalmers University of Technology in Sweden is about to enter a new field of research - biological physics. The aim is to develop biomedical instruments and methods for basic research and for applications within pharmaceutical development and medical diagnostics. Professor Fredrik Höök has been recruited by Chalmers to head this research group.

Professor Höök, who for the past three years has been Professor of Nanoscience for Biophysics at Lund University, is just one in a series of recruitments which Chalmers has made within bioscience. This time the base is in physics and is linked to current research within materials science and nanotechnology. Fredrik Höök is also an entrepreneur and is expected to become a key link between Chalmers and the biotechnology industry in Sweden.

"Chalmers is building on the already successful environment in applied physics. Fredrik Höök's work represents yet another step towards satisfying needs and realising potential within biology and medical applications. The interface between natural science, engineering and medicine can benefit from the unique conditions that exist in Gothenburg. This is expected to lead to new technologies and innovations which could reinforce Swedish healthcare and industry even further. I am convinced that Fredrik Höök will capitalise on these opportunities and develop them optimally together with his fellow researchers," says Chalmers President Karin Markides.

Fredrik Höök's research deals with the development of instrumentation and techniques for improved diagnostics and pharmaceutical development. As a PhD student at Chalmers he was involved in founding the company Q-Sense, which manufactures and sells measuring instruments which are used throughout the world by researchers at universities and hospitals as well as developers in industry. The instruments are used primarily to study how biomolecules interact with different materials, which is a key component in the development of diagnostic sensors. Some years after taking his PhD he was offered a professorship in Lund, where his research group developed a completely new method for analysing membrane proteins.

... more about:
»AIM »Diagnostic »Fredrik »Höök »Pharmaceutical »Physics

"We are seeking to use new concepts within nanotechnology coupled with the most recent advances in molecular biology to develop more effective sensors and analysis instruments. The aim is more rapid detection of diseases at an earlier stage. We want to improve existing clinical instruments and develop new ones in order to increase accuracy and reduce cost. Our instruments should be available for use at companies working on pharmaceutical development as well as in hospitals for diagnostic purposes," says Fredrik Höök.

The aim of the research group is to detect disease markers on the individual molecule level. At present, millions of molecules are often needed in a blood sample in order to confirm a disease.

Strong research at Chalmers within areas such as soft materials, supermolecular chemistry and biological imaging will be a significant advantage. Co-operation with the Chalmers Biocentre and Sahlgrenska University Hospital will also make it possible to get even closer to the fundamentals of biology and medicine in a completely new way.

Fredrik Höök feels that world-class research in itself is not enough:

"We have worked our way through to the research front line. The aim now is to get past it and become the leader in the field although we will not succeed in this as an independent research group. We must co-operate with several different disciplines.

As a spin-off from our research we have learnt a great deal about cell membranes and how they melt together. This knowledge is vital within pharmaceutical distribution - a new field of interest for us. It is possible to deal with diseases in a completely new way one you have succeeded in getting past the barrier which the membrane represents and can send the drug directly into the diseased cells. Nature has already solved this in the marvellous process where a sperm and an egg merge. We want to learn how to make use of that principle so that one day we can deliver a drug directly to a predetermined place in the body, such as a cancer cell."

He will also bring with him to Chalmers a research group which will be integrated with the biologically oriented work previously led by Bengt Kasemo at the Department of Chemical Physics.

"There will be a broad range of expertise in the group. We are looking forward to working with different researchers at Chalmers, such as physicists, chemists, bioengineers and electrical engineers. The most gratifying aspect of my work is working with young people with a thirst for knowledge. I also hope to make a strong contribution to undergraduate education at Chalmers."

Contact and more information: Fredrik Höök +46-31 772 61 09; fredrik.hook@chalmers.se

Pressofficer Sofie Hebrand; sofie.hebrand@chalmers.se; +46 736-79 35 90

Sofie Hebrand | idw
Further information:
http://www.vr.se

Further reports about: AIM Diagnostic Fredrik Höök Pharmaceutical Physics

More articles from Life Sciences:

nachricht World’s Largest Study on Allergic Rhinitis Reveals new Risk Genes
17.07.2018 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt

nachricht Plant mothers talk to their embryos via the hormone auxin
17.07.2018 | Institute of Science and Technology Austria

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First evidence on the source of extragalactic particles

For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.

To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...

Im Focus: Magnetic vortices: Two independent magnetic skyrmion phases discovered in a single material

For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.

Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...

Im Focus: Breaking the bond: To take part or not?

Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.

A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...

Im Focus: New 2D Spectroscopy Methods

Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.

"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....

Im Focus: Chemical reactions in the light of ultrashort X-ray pulses from free-electron lasers

Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.

Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Leading experts in Diabetes, Metabolism and Biomedical Engineering discuss Precision Medicine

13.07.2018 | Event News

Conference on Laser Polishing – LaP: Fine Tuning for Surfaces

12.07.2018 | Event News

11th European Wood-based Panel Symposium 2018: Meeting point for the wood-based materials industry

03.07.2018 | Event News

 
Latest News

Microscopic trampoline may help create networks of quantum computers

17.07.2018 | Information Technology

In borophene, boundaries are no barrier

17.07.2018 | Materials Sciences

The role of Sodium for the Enhancement of Solar Cells

17.07.2018 | Power and Electrical Engineering

VideoLinks
Science & Research
Overview of more VideoLinks >>>