Improved Therapy of myocardial infarction?

This is the result of a clinical study recently reported by a group of scientists from the University Duisburg-Essen (UDE) in Circulation Research, the official journal of the American Heart Association.

A team of researchers from the Institute of Pathophysiology, the Clinic of Cardiothoracic Surgery and the Clinic of Anesthesiology, which was led by Professor Gerd Heusch, found such protection of the heart at a distance.

They first identified STAT5 as a protective molecular signal in the human heart. STAT signals improve the function of mitochondria, i.e. the cellular powerplants, and reduce the size of a myocardial infarction in the experiment.

In a myocardial infarction, parts of the cardiac muscle receive no blood supply because the coronary vessels are occluded. Cardiovascular disease is the most frequent cause of death in Germany, and 70.000 people annually die from myocardial infarction in Germany. The basic and translational research of Prof. Heusch on protection of the heart from infarction is supported by the German Research Foundation.

Further Informations:
• http://circres.ahajournals.org/content/110/1/111
• Prof. Dr. Dr.h.c. Gerd Heusch, phone. +49 201 723 4480,
gerd.heusch@uk-essen.de
Editorial Office: Beate H. Kostka, phone: +49 203 379 2430

Media Contact

Beate Kostka idw

All news from this category: Health and Medicine

This subject area encompasses research and studies in the field of human medicine.

Among the wide-ranging list of topics covered here are anesthesiology, anatomy, surgery, human genetics, hygiene and environmental medicine, internal medicine, neurology, pharmacology, physiology, urology and dental medicine.

Back to the Homepage

Comments (0)

Write comment

Latest posts

Optically Active Defects Improve Carbon Nanotubes

Heidelberg scientists achieve defect control with a new reaction pathway. The properties of carbon-based nanomaterials can be altered and engineered through the deliberate introduction of certain structural “imperfections” or defects….

Visualizing the motion of vortices in superfluid turbulence

Nobel laureate in physics Richard Feynman once described turbulence as “the most important unsolved problem of classical physics.” Understanding turbulence in classical fluids like water and air is difficult partly…

Toward a reliable oral treatment for sickle cell disease

For the millions of people worldwide who have sickle cell disease, there are only a few treatment options, which include risky bone marrow transplants, gene therapy or other treatments that…

Partners & Sponsors