Scaffold-stabilized L2 peptides as HPV vaccine
The thioredoxin-L2 vaccines consist of thioredoxin as a “scaffold” protein and one of several L2 peptide concatemers. The most effective peptides have been identified by epitope mapping; a positive corre-lation of the number of peptide units in the
concatemer with the titer of neutralizing antibodies has been shown.
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