Hyalurinic Acid with Cytokines –for Treatment of Osteoarthritis
<strong>Background</strong><br>
The intraarticular injection of hyaluronic acid (HA) in patients with osteoarthri-tis is so far the most promising treatment as it has been shown to delay the degeneration of cartilage. Even though it is known that the transplantation of stem and progenitor cells into degenerated tissue stimulates the regeneration of the damaged tissue there is still no treatment available which successfully regenerates the damaged tissue. <br><br> <strong>Technology</strong><br> The intraarticular injection of a suspension comprising HA and chemokine-loaded microparticles delay cartilage degeneration while stimulating the re-generation of the damaged tissue. The synergistic effect of HA on the re-cruitment of stem and progenitor cells by chemoattractants has been proven to promote tissue regeneration. <br><br> <strong>Benefits</strong> <ul> <li>Stimulation of cartilage regeneration </li> <li>Local cytokine release </li> <li>Biocompatible and biodegradable microparticles</li> </ul> <p><strong>IP Rights</strong><br> German patent application (12/2010)<br> PCT application (11/2011) <br> <br> <strong>Patent Owner</strong><br> Charité – Universitätsmedizin Berlin
Further Information: PDF
ipal GmbH
Phone: +49 (0)30/2125-4820
Contact
Dr. Dirk Dantz
Media Contact
All latest news from the category: Technology Offerings
Newest articles
Roadmap to close the carbon cycle
A holistic approach to reach net-zero carbon emissions across the economy. A major approach to achieving net-zero carbon emissions relies on converting various parts of the economy, such as personal…
Cost-effective, high-capacity, and cyclable lithium-ion battery cathodes
Charge-recharge cycling of lithium-superrich iron oxide, a cost-effective and high-capacity cathode for new-generation lithium-ion batteries, can be greatly improved by doping with readily available mineral elements. The energy capacity and…
New regulator of eating behaviour identified
The rapidly escalating prevalence of overweight and obesity poses a significant medical challenge worldwide. In addition to people’s changing lifestyles, genetic factors also play a key role in the development…