CCL17 AS CENTRAL IMMUNE REGULATOR – CCL17 INHIBITORS FOR USE IN T HELPER CELL-DRIVEN DISEASES
The current invention is based on the identification of the role of CCL17 in the genesis of T helper cell Th1-driven diseases, in particular atherosclerosis and autoimmune diseases.
The invention provides novel therapeutic approaches for treating atherosclerosis and other diseases such as myocardial infarction, stroke, peripheral vascular disease, chronic kidney disease and angina pectoris. These approaches are based on interfering with the interaction between the CCL17-cytokine and the CCL17-receptor. Respective agents will also be beneficial for the treatment of autoimmune diseases e.g. hypersensitivity dermatitis (CHS), psoriasis, rheumatoid arthritis, Bechterew's disease and inflammatory bowel disease (Crohn`s disease).
Further Information: PDF
PROvendis GmbH
Phone: +49 (0)208/94105 10
Contact
Dipl.-Ing. Alfred Schillert
Media Contact
All latest news from the category: Technology Offerings
Newest articles
Sea slugs inspire highly stretchable biomedical sensor
USC Viterbi School of Engineering researcher Hangbo Zhao presents findings on highly stretchable and customizable microneedles for application in fields including neuroscience, tissue engineering, and wearable bioelectronics. The revolution in…
Twisting and binding matter waves with photons in a cavity
Precisely measuring the energy states of individual atoms has been a historical challenge for physicists due to atomic recoil. When an atom interacts with a photon, the atom “recoils” in…
Nanotubes, nanoparticles, and antibodies detect tiny amounts of fentanyl
New sensor is six orders of magnitude more sensitive than the next best thing. A research team at Pitt led by Alexander Star, a chemistry professor in the Kenneth P. Dietrich…
