Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Phosphate Binder for the Treatment of Hyperphosphatemia

10.01.2013
<strong>Background</strong><br>

Hyperphosphatemia is a complication of chronic kidney disease. Patients with renal insufficiency have an abnormal phosphate metabolism that leads to an elevated concentration of phosphate in the blood. In conjunction with calcium imbalance, hyperphosphatemia increases the risk of cardiovascular disease in patients with renal failure. Hyperphosphatemia promotes arterial calcification which increases the risk of myocardial infarction and is therefore a big risk factor for cardiovascular mortality in dialysis patients. Due to the problems of current phosphate binders like poor taste, halitosis, gastro-intestinal complaints and high cost, there is a great demand for novel phosphate binders.<br><br> <strong>Technology</strong><br> We offer a phosphate binder on the basis of maghemite or maghemite/ magnetite. The novel phosphate binder comprises an iron oxide core being coated with carbohydrates e.g. sugar molecules like mannose or fructan. The iron oxide core is less than 20 nm in diameter and shows an inverse spinel structure, which offers a high phosphate binding capacity. <br><br>

<strong>Benefits</strong> <ul> <li>Highly improved phosphate binding capacity</li> <li>Well tolerated oral phosphate binder</li> <li>No known side effects</li> <li>Low manufacturing costs</li> <li>Easy to manufacture </li> </ul> <p><strong>IP Rights</strong><br> DE, US patent application (09/2011)<br> PCT patent application <br> <br> <strong>Patent Owner</strong><br> Charité Universitätsmedizin Berlin</p>

Further Information: PDF

ipal GmbH
Phone: +49 (0)30/2125-4820

Contact
Dr. Dirk Dantz

info@technologieallianz.de | TechnologieAllianz e.V.
Further information:
http://www.technologieallianz.de/angebote.php?sort=sag&id=2978&lang=en
http://www.technologieallianz.de

More articles from Technology Offerings:

nachricht New Lithium Salts of Pentafluorophenylamide Anions as Electrolytes in Lithium Ionic Batteries
18.04.2017 | TechnologieAllianz e.V.

nachricht Gratings on glass surfaces
28.03.2017 | TechnologieAllianz e.V.

All articles from Technology Offerings >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

Im Focus: On the way to a biological alternative

A bacterial enzyme enables reactions that open up alternatives to key industrial chemical processes

The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....

Im Focus: The 1 trillion tonne iceberg

Larsen C Ice Shelf rift finally breaks through

A one trillion tonne iceberg - one of the biggest ever recorded -- has calved away from the Larsen C Ice Shelf in Antarctica, after a rift in the ice,...

Im Focus: Laser-cooled ions contribute to better understanding of friction

Physics supports biology: Researchers from PTB have developed a model system to investigate friction phenomena with atomic precision

Friction: what you want from car brakes, otherwise rather a nuisance. In any case, it is useful to know as precisely as possible how friction phenomena arise –...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

 
Latest News

NASA looks to solar eclipse to help understand Earth's energy system

21.07.2017 | Earth Sciences

Stanford researchers develop a new type of soft, growing robot

21.07.2017 | Power and Electrical Engineering

Vortex photons from electrons in circular motion

21.07.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>