Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Agent for optimizing fertilization media - Fetuin-B as an essential agent for in vitro fertilization

Fetuin-B is necessary for fertilization. Scientists of the RWTH Aachen University discovered, that this liver-derived plasma protein sustains fertility by inhibiting ovastacin, a cortical granula protease known to trigger zona pellucida (ZP) hardening. ZP hardening prevents sperm from binding to and penetrating the ZP.

Prior to gamete fusion, sperm are able to bind and penetrate the ZP. Upon fertilization ZP hardening occurs. But in vitro, ZP hardening regularly occurs even without sperm binding, thereby preventing fertilization. Women who cannot become pregnant naturally or who must not become pregnant at a specific time for medical reasons, e. g. cancer treatment, it is important to maintain the fertilizable state of an isolates oocyte. Experiments demonstrate that Fetuin-B plays an important role in the maturation of oocytes: It prevents premature hardening of ZP of oocytes after their isolation from a female body. The invention offers a solution to the problem of premature ZP hardening, i.e. adding Fetuin-B to fertilization media for in vitro fertilization (IVF) procedures. Addition of Fetuin-B to such media will maintain fertility of oocytes after isolation from a woman and during preservation in a fertilizable stage for future processing and use.

Further Information: PDF

PROvendis GmbH
Phone: +49 (0)208/94105 10

Dipl.-Ing. Alfred Schillert | TechnologieAllianz e.V.
Further information:

More articles from Technology Offerings:

nachricht Method and Device for Two-Dimensional Separation of Ionic Species
27.10.2016 | TechnologieAllianz e.V.

nachricht Shaft power plant
27.10.2016 | TechnologieAllianz e.V.

All articles from Technology Offerings >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Novel light sources made of 2D materials

Physicists from the University of Würzburg have designed a light source that emits photon pairs. Two-photon sources are particularly well suited for tap-proof data encryption. The experiment's key ingredients: a semiconductor crystal and some sticky tape.

So-called monolayers are at the heart of the research activities. These "super materials" (as the prestigious science magazine "Nature" puts it) have been...

Im Focus: Etching Microstructures with Lasers

Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.

This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Prototype device for measuring graphene-based electromagnetic radiation created

28.10.2016 | Power and Electrical Engineering

Gamma ray camera offers new view on ultra-high energy electrons in plasma

28.10.2016 | Physics and Astronomy

When fat cells change their colour

28.10.2016 | Life Sciences

More VideoLinks >>>