Pain may interfere with depression improvement
Treatment for depression may be stymied in people with moderate to severe body pain, according to a new study.
Researchers Matthew J. Bair, M.D., formerly of the Regenstrief Institute, and colleagues uncovered the connection by analyzing the results of a clinical trial of 573 depression patients taking medications like Prozac, Paxil or Zoloft. Their findings are published in the journal Psychosomatic Medicine.
Although depression improved in most of the patients after three months of drug therapy, 24 percent had persistently high depression scores. The therapy was most likely to fail among those who reported moderate to severe pain at the beginning of their treatment.
“In particular, the odds of a poor depression treatment response were twice as high in patients with moderate pain at baseline and three to four times as high in those with severe pain,” Bair says.
Factors like pain may help explain why antidepressants have a mixed record of success, Bair says. Between 50 and 70 percent of depressed patients find only partial relief with their medications.
Researchers have long known that pain and depression often go hand in hand, but there are few studies of how pain might affect depression treatment. In the Bair study, more than two-thirds of the patients reported some degree of pain at the start of their treatment. Twenty-five percent said their pain was mild, 30 percent had moderate pain and 14 percent said they had severe pain.
“We believe a treatment model that incorporates assessment and treatment of both depression and pain is desirable,” Bair says.
The study was supported by the Health Resources and Service Administration and Eli Lilly and Co.
Health Behavior News Service: (202) 387-2829 or www.hbns.org.
Interviews: Contact Matthew Bair at email@example.com.
Psychosomatic Medicine: Contact Victoria White at (352) 376-1611, ext. 5300, or firstname.lastname@example.org. Online, visit www.psychosomaticmedicine.org.
Becky Ham | Health Behavior News Service
The most recent press releases about innovation >>>
Die letzten 5 Focus-News des innovations-reports im Überblick:
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Mapping the interaction of a single atom with a single photon may inform design of quantum devices
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...