Research indicates no justification for denying obese patients knee replacements
Research by scientists at the MRC Epidemiology Resource Centre at the University of Southampton, in collaboration with colleagues at the universities of Bristol, Oxford and Keele, has shown that there is no justification for denying obese patients knee replacement surgery
The research, published online in the journal Annals of the Rheumatic Diseases, shows that clinically obese people (those who have a body mass index (BMI) of above 30 kg/m2) can benefit almost as much as anyone else from the procedure.
Around 55,000 knee replacements are performed each year in England to relieve the pain and disability of knee osteoarthritis. However, in some parts of the country, surgery is offered only to patients who are not clinically obese on the grounds that obesity is itself a risk factor for knee osteoarthritis.
The research team reached its conclusions following a six-year study of two groups of people, all over the age of 45. The first group (325 people) had all had knee replacement surgery and the second group (363 people) had not. At the start and end of the study, all participants completed a validated questionnaire designed to assess their mobility, mental health and wellbeing.
The findings showed that, overall, the mobility of those who had had knee replacement surgery improved over the six years of the study, while it fell in the comparison group. When researchers restricted their analysis to those participants who were obese, improvements in mobility appeared to persist and BMI was not a significant predictor of this improvement.
Professor Cyrus Cooper, Director of the ERC and Professor of Rheumatology at the University of Southampton, said: "The long-term improvement in physical function that we observed in patients who have undergone knee replacement surgery is striking when set against the decline that occurred in the comparison group.
"These benefits extended to those patients who were clinically obese. Our results show that as long as appropriate selection criteria are applied with regard to fitness for surgery, there seems little justification for withholding the operation from patients who are obese."
Research paper: Long term outcome following total knee arthoplasty: a controlled longitudinal study
Online First Ann Rheum Dis 2008; doi 10.1136/ard.2008.093229]
Sarah Watts | alfa
The most recent press releases about innovation >>>
Die letzten 5 Focus-News des innovations-reports im Überblick:
An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.
Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...
Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.
Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...
Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.
As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...
Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.
With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...
Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine
Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...