Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Research indicates no justification for denying obese patients knee replacements

21.08.2008
Research by scientists at the MRC Epidemiology Resource Centre at the University of Southampton, in collaboration with colleagues at the universities of Bristol, Oxford and Keele, has shown that there is no justification for denying obese patients knee replacement surgery

The research, published online in the journal Annals of the Rheumatic Diseases, shows that clinically obese people (those who have a body mass index (BMI) of above 30 kg/m2) can benefit almost as much as anyone else from the procedure.

Around 55,000 knee replacements are performed each year in England to relieve the pain and disability of knee osteoarthritis. However, in some parts of the country, surgery is offered only to patients who are not clinically obese on the grounds that obesity is itself a risk factor for knee osteoarthritis.

The research team reached its conclusions following a six-year study of two groups of people, all over the age of 45. The first group (325 people) had all had knee replacement surgery and the second group (363 people) had not. At the start and end of the study, all participants completed a validated questionnaire designed to assess their mobility, mental health and wellbeing.

The findings showed that, overall, the mobility of those who had had knee replacement surgery improved over the six years of the study, while it fell in the comparison group. When researchers restricted their analysis to those participants who were obese, improvements in mobility appeared to persist and BMI was not a significant predictor of this improvement.

Professor Cyrus Cooper, Director of the ERC and Professor of Rheumatology at the University of Southampton, said: "The long-term improvement in physical function that we observed in patients who have undergone knee replacement surgery is striking when set against the decline that occurred in the comparison group.

"These benefits extended to those patients who were clinically obese. Our results show that as long as appropriate selection criteria are applied with regard to fitness for surgery, there seems little justification for withholding the operation from patients who are obese."

Research paper: Long term outcome following total knee arthoplasty: a controlled longitudinal study

Online First Ann Rheum Dis 2008; doi 10.1136/ard.2008.093229]

Sarah Watts | alfa
Further information:
http://www.soton.ac.uk

More articles from Health and Medicine:

nachricht Vanishing capillaries
23.03.2017 | Technische Universität München

nachricht How prenatal maternal infections may affect genetic factors in Autism spectrum disorder
22.03.2017 | University of California - San Diego

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

When Air is in Short Supply - Shedding light on plant stress reactions when oxygen runs short

23.03.2017 | Life Sciences

Researchers use light to remotely control curvature of plastics

23.03.2017 | Power and Electrical Engineering

Sea ice extent sinks to record lows at both poles

23.03.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>