“A V/Q scan can be the first choice—but the CT angiogram is the classic choice—for diagnosing a pulmonary embolism,” noted H. Dirk Sostman, a professor of radiology and executive vice dean at Weill Cornell Medical College in New York City and chief academic officer at the Methodist Hospital in Houston, Texas. “A ‘very low probability’ V/Q lung scan—together with a ‘low probability’ objective clinical assessment—is as reliable as a CT angiogram and allows a doctor to evaluate whether a pulmonary embolism is present or not,” added Alexander Gottschalk, a professor of diagnostic radiology at Michigan State University in East Lansing.
A noninvasive V/Q scan involves two tests using radioactive material to measure breathing (ventilation) and circulation (perfusion) in all areas of the lungs, said Gottschalk, who has performed research with studies like the Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED) project for more than 30 years. V/Q scans reduce the radiation to the breast by about 70 times on average compared to higher-radiation procedures such as computed tomography pulmonary angiography (CTA), he explained.
“While CTA is the major test used widely to detect pulmonary embolisms, it is associated with higher radiation risk, especially for young women of reproductive age,” said Gottschalk. “The combination of a low probability V/Q scan and low probability clinical assessment is extremely effective,” said Sostman. “Our study is important for doctors—and their patients—since tests show that high radiation doses to the breast from CT, especially important in young women, may increase their risk of breast cancer,” he added.
A pulmonary embolism is a sudden blockage in a lung artery, usually occurring when a blood clot travels to the lung from a vein in the leg. This condition can cause permanent damage to a part of the lung. And, if a blood clot is large—or if they are numerous—a pulmonary embolism can cause death. According to statistics, at least 100,000 cases of pulmonary embolism take place each year in this country, and it is considered the third most common cause of death in hospitalized patients. A person’s risk at getting a pulmonary embolism doubles every 10 years after the age of 60.
In their study, Gottschalk and Sostman analyzed the prospectively gathered data from PIOPED II, a large-scale, multicenter trial. “Very Low Probability Interpretation of Ventilation Perfusion Lung Scans in Combination With Low Probability Objective Clinical Assessment Reliably Excludes Pulmonary Embolism: Data From PIOPED II” appears in the September issue of the Journal of Nuclear Medicine, which is published by SNM, the world’s largest molecular imaging and nuclear medicine society. Additional co-authors include Paul D. Stein, St. Joseph Mercy Oakland Hospital, Pontiac, Mich., Wayne State University, Detroit, Mich.; and Fadi Matta and Afzal Beemath, St. Joseph Mercy Oakland Hospital, Pontiac, Mich.
Media representatives: To obtain a copy of this article, please contact Maryann Verrillo by phone at (703) 652-6773 or send an e-mail to firstname.lastname@example.org. Current and past issues of the Journal of Nuclear Medicine can be found online at jnm.snmjournals.org. Print copies can be obtained by contacting the SNM Service Center, 1850 Samuel Morse Drive, Reston, VA 20190-5316; phone (800) 513-6853; e-mail email@example.com; fax (703) 708-9015. A subscription to the journal is an SNM member benefit.
About SNM—Advancing Molecular Imaging and Therapy
SNM is an international scientific and professional organization of more than 16,000 members dedicated to promoting the science, technology and practical applications of molecular and nuclear imaging to diagnose, manage and treat diseases in women, men and children. Founded more than 50 years ago, SNM continues to provide essential resources for health care practitioners and patients; publish the most prominent peer-reviewed journal in the field (Journal of Nuclear Medicine); host the premier annual meeting for medical imaging; sponsor research grants, fellowships and awards; and train physicians, technologists, scientists, physicists, chemists and radiopharmacists in state-of-the-art imaging procedures and advances. SNM members have introduced—and continue to explore—biological and technological innovations in medicine that noninvasively investigate the molecular basis of diseases, benefiting countless generations of patients. SNM is based in Reston, Va.; additional information can be found online at http://www.snm.org.
Maryann Verrillo | EurekAlert!
Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign
Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
20.01.2017 | Awards Funding
20.01.2017 | Materials Sciences
20.01.2017 | Life Sciences