Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Dipyrone may treat headaches – but use with caution: New Findings from The Cochrane Library

18.04.2007
The controversial drug dipyrone can treat acute headaches, but patients should be warned of the risk of potentially serious blood disorders (or “dyscrasias”), concluded a Cochrane Review team. Furthermore, most of the studies used in reaching this conclusion involved intravenous infusions of the drug, making it expensive and complex to deliver.

Dipyrone is a non-opioid painkiller that was launched in Germany in 1922 but was later banned from many countries including the USA and UK because of evidence that it might cause life-threatening blood disorders such as agranulocytosis. It is, however, a popular analgesic in many parts of the world including South America, India, South Africa, Russia and several European countries. Oral doses can be bought over the counter in Brazil and Spain.

A group of Cochrane Researchers set out to evaluate whether dipyrone was effective and safe for acute primary headaches in adults and children.

They identified four trials that involved 636 adults. None involved children. Three of the studies used intravenous dipyrone.

Taken together the evidence indicates that dipyrone is effective in treating episodic tension-type headaches and migraine in adults. The sample size, however, was too small to make any assessment of the medicine’s safety.

“Given that many effective and more easily administered therapies are available, patients and clinicians will need to consider whether and in what circumstances the benefits of treatment are worth the time, trouble and expense of intravenous administration,” says Dr Rebecca Gray, a Cochrane Editor who worked closely with the project.

If used, “patients should be well informed about the risk of blood dyscrasias,” she adds.

Jennifer Beal | alfa
Further information:
http://www.thecochranelibrary.com

More articles from Health and Medicine:

nachricht New vaccine production could improve flu shot accuracy
25.07.2017 | Duke University

nachricht Chances to treat childhood dementia
24.07.2017 | Julius-Maximilians-Universität Würzburg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Carbon Nanotubes Turn Electrical Current into Light-emitting Quasi-particles

Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers

Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...

Im Focus: Flexible proximity sensor creates smart surfaces

Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.

At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...

Im Focus: 3-D scanning with water

3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects

A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

 
Latest News

NASA mission surfs through waves in space to understand space weather

25.07.2017 | Physics and Astronomy

Strength of tectonic plates may explain shape of the Tibetan Plateau, study finds

25.07.2017 | Earth Sciences

The dense vessel network regulates formation of thrombocytes in the bone marrow

25.07.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>