Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New technique in permanent bradytherapy for the treatment of lung cancer

09.07.2004


The University Hospital at Navarre University has developed a system for the percutaneous implantation of palladium 103 seeds, a new technique in permanent bradytherapy for the treatment of lung cancer. Recently, the fourth experiment was carried out and the results remitted to the scientific magazine, "Bradytherapy", for its publication. To date there has been no description in world scientific literature of any case using this therapeutic procedure.



The Clínica Universitaria has hosted the only cases of bradytherapy using palladium implantation although, in the literature, there exist two articles on the treatment of 8 patients with iodine 125, a radioisotope especially suited to treatment of prostate cancer. In this case it was decided to opt for palladium 103 given that theoretically it adapts better to rapid and aggressive growth lesions such as the majority of primary lung tumours – although this affirmation is not backed up by clinical data. Apart from this, the isotope having a shorter half-life, the radiological protection measures are reduced.

Bradytherapy is a radical radiation technique which is undertaken jointly by the Radiology and Oncology Departments at the University Hospital. It involves the percutaneous implantation of radioactive seeds by means of vectors that are placed inside the tumour. The procedure is carried out under a general anaesthetic with the patient lying on their back. First, the radiologist selects the target area and then the vectors are introduced with the point guided by CAT (computer-controlled axial tomography); in this way the structures through which they pass can be seen in practically real time. Once it is confirmed that the vectors are correctly placed into position, the radioactive load is impanted.


Suitability

Bradytherapy with palladium 103 is suitable for those persons with small lesions which, because they are deemed medically unsuitable (because of age, accompanying illnesses, limited pulmonary capacity, etc.), cannot be subjected to open surgery involving the resection of lung tissue. They are very select, high-risk patients who have tumours accessible at the point of puncture by an external route. Until now, the only alternative therapy available to these patients has been external radiation. Nevertheless, this treatment has the drawback of lasting possibly weeks, whereas Bradytherapy is carried out in just one day.

The results obtained with this technique are very satisfactory although not definitive, given the short period of monitoring. Apart from these data, in the opinion of Dr. Martínez-Monge, Bradytherapy has demonstrated its success as a therapeutic option for this group of patients who cannot undergo surgery.

Given that the implantation of palladium 103 is carried out in a percutaneous manner, this technique provides the advantage of a rapid recovery without pain. Moreover, the only two possible complications (pneumothorax, i.e. entry of air into the thoracic cavity and the risk of bleeding) are verified in situ, which allows a rapid response. In any case, none of the patients treated with this procedure has shown these complications nor have others been observed.

Garazi Andonegi | Basque Research
Further information:
http://www.unav.es

More articles from Health and Medicine:

nachricht Hot cars can hit deadly temperatures in as little as one hour
24.05.2018 | Arizona State University

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

When corals eat plastics

24.05.2018 | Ecology, The Environment and Conservation

Surgery involving ultrasound energy found to treat high blood pressure

24.05.2018 | Medical Engineering

First chip-scale broadband optical system that can sense molecules in the mid-IR

24.05.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>