Fox Chase Cancer Center researchers have demonstrated the ability to identify kidney cancer, including localized (stage I) cancer, in the urine of affected patients. Whats more, urine tests were repeated following the removal of the cancerous kidney and none of the tests showed DNA evidence of disease. These research findings were presented at the American Urological Association Annual Meeting May 8-13, 2004 in San Francisco.
As with other cancers, an early diagnosis of kidney cancer can result in curative treatment whereas the prognosis for advanced kidney cancer is poor. The challenge in diagnosing cancer early is developing an inexpensive, noninvasive, accurate and simple screening test. A urine test meets these standards.
"We used a common laboratory procedure to test the urine of 50 patients with kidney cancer," explained Fox Chase molecular biologist Paul Cairns, Ph.D. "Forty-four of the 50 tests showed gene changes in the urine that were identical to the gene changes found in the tumor tissue taken at the time of surgery."
Karen C. Mallet | EurekAlert!
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