Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Heat zapps bone tumors

13.05.2003


A team of radiologists and orthopedic specialists at Johns Hopkins Medicine has successfully used heat generated by electrode-tipped probes to destroy painful, benign bone tumors in eight of nine patients in a clinical study.



The results of the study, published in the March issue of the Journal of Vascular Interventional Radiology, suggests a need for further research to confirm the effectiveness of percutaneous radiofrequency for treating osteoid osteomas.

In the study, all eight patients achieved complete pain relief after thin probes were inserted through the skin into the core of the bone tumor, and radiofrequency energy was used to produce enough heat to destroy the tumor at its biological core. Five patients underwent the procedure with guidance provided by a new type of fast CT scanner incorporating CT fluoroscopy at 13 frames a second in three places at once.


Osteoid osteomas account for up to 12 percent of all benign bone tumors and occur primarily in children and young adults, according to Kieran Murphy, M.D., director of neurointerventional radiology at Hopkins and a member of the study team. While not life-threatening, the tumors can be extremely painful.

Standard treatment consists of nonsteroidal anti-inflammatory drugs. However, when pain is severe and/or long-term conventional drug treatment causes complications, surgical removal is the usual alternative.

Murphy notes that while the reported success rate for such surgery is very high, it carries some risks. "Depending on the size of the bone tumor, bone fractures can occur at the site of the tumor removal and bone grafting may be required," he says.

While all eight of the patients benefitted, three achieved success only after re-treatment. Initial failures were attributed to the use of fluoroscopy alone for tumor localization, which provided less precise tumor images than did CT fluoroscopy. One patient eventually required surgical removal of the tumor to achieve complete pain relief. No immediate or delayed complications were observed in any of the patients treated.

"Based on these early results, it appears that CT fluoroscopy offers the most precise imaging method for localizing the most critical area of the tumor in which to place the heat probe," says Murphy. "Combining the minimally invasive approach of radiofrequency ablation and the enhanced imaging guidance of CT fluoroscopy gives us a potentially powerful new alternative for treating these tumors."

Gary Stephenson | EurekAlert!
Further information:
http://www.hopkinsmedicine.org/

More articles from Health and Medicine:

nachricht Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University

nachricht The first analysis of Ewing's sarcoma methyloma opens doors to new treatments
01.12.2016 | IDIBELL-Bellvitge Biomedical Research Institute

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

Im Focus: Molecules change shape when wet

Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water

In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

NASA's AIM observes early noctilucent ice clouds over Antarctica

05.12.2016 | Earth Sciences

Shape matters when light meets atom

05.12.2016 | Physics and Astronomy

Researchers uncover protein-based “cancer signature”

05.12.2016 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>