Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Small But Super

31.05.2010
Lightweight, handy magnets for portable NMR spectrometers

High-resolution nuclear magnetic resonance (NMR) spectrometry is one of the most powerful analytical tools for the precise determination of molecular structures and dynamics.

To attain a high resolution, very strong magnetic fields are required, which are produced by superconducting electromagnets. Federico Casanova and his co-workers at the RWTH In Aachen (Germany) have now developed a light, permanent magnet that is suitable for NMR and fits in the palm of your hand. As the researchers report in the journal Angewandte Chemie, this could represent the cornerstone for portable, high-resolution NMR instruments.

In the 1960s and 1970s, NMR spectrometers used permanent magnets, which were not as massive as the superconducting magnets used today. With modern, improved permanent magnets, it should theoretically be possible to build handy, robust devices. This would make it possible to obtain NMR spectra that are about a third as sensitive as those obtained with standard-sized superconducting magnets. “This would be an acceptable concession for a small and portable NMR system,” says Casanova. “However, there is one problem: As the magnet gets smaller, the dimensions of the homogenous (uniform) magnetic field also decrease, making the sample volume smaller. Reduction of the sample volume affects the signal-to-noise ratio.”

The Aachen team has now developed a small permanent magnet weighing only 500 g with an unusually homogenous magnetic field that allows a standard-sized NMR tube to be used. Their success is due to a Halbach array: individual magnetic blocks are assembled into a cylinder so that the direction of their magnetization is tuned to produce an especially homogenous field within the cylinder. The researchers connect three Halbach rings whose diameter is optimized to compensate for the distortion of the magnetic field at the ends of the cylindrical inner chamber. In this way a sufficiently large homogenous magnetic field is produced inside the cylinder, which is large enough for a standard NMR tube. To even out the inhomogeneities originating from the granularity of the magnetic material, each ring consists of trapezoidal magnetic blocks with gaps in between. Inside the gaps are rectangular magnetic blocks that can be displaced radially to mechanically adjust (“shim”) the magnetic field.

“Spectra we obtained show that our miniature magnet is suitable for high-resolution NMR spectroscopy with standard-sized sample tubes,” reports Casanova. “It would be easy to transport together with the spectrometer. This could allow high-resolution NMR spectroscopy to develop into a portable analytical technique for use on samples in the field.”

Author: Federico Casanova, RWTH Aachen (Germany), http://www.mc.rwth-aachen.de/

Title: Small Magnets for Portable NMR Spectrometers

Angewandte Chemie International Edition 2010, 49, No. 24, 4133–4135, Permalink to the article: http://dx.doi.org/10.1002/anie.201000221

Federico Casanova | Angewandte Chemie
Further information:
http://www.mc.rwth-aachen.de/
http://pressroom.angewandte.org

More articles from Life Sciences:

nachricht Flow of cerebrospinal fluid regulates neural stem cell division
22.05.2018 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt

nachricht Chemists at FAU successfully demonstrate imine hydrogenation with inexpensive main group metal
22.05.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

Im Focus: Computer-Designed Customized Regenerative Heart Valves

Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.

Producing living tissue or organs based on human cells is one of the main research fields in regenerative medicine. Tissue engineering, which involves growing...

Im Focus: Light-induced superconductivity under high pressure

A team of scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg investigated optically-induced superconductivity in the alkali-doped fulleride K3C60under high external pressures. This study allowed, on one hand, to uniquely assess the nature of the transient state as a superconducting phase. In addition, it unveiled the possibility to induce superconductivity in K3C60 at temperatures far above the -170 degrees Celsius hypothesized previously, and rather all the way to room temperature. The paper by Cantaluppi et al has been published in Nature Physics.

Unlike ordinary metals, superconductors have the unique capability of transporting electrical currents without any loss. Nowadays, their technological...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Supersonic waves may help electronics beat the heat

18.05.2018 | Power and Electrical Engineering

Keeping a Close Eye on Ice Loss

18.05.2018 | Information Technology

CrowdWater: An App for Flood Research

18.05.2018 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>