The long molecules of DNA that carry our genetic information are wrapped up together with proteins into a dense complex called chromatin. The structure of chromatin is dynamic and varies according to different phases of a cell’s life, a phenomenon that is called chromatin plasticity. Chromatin structure plays a critical role in regulating our genes and research in this area has the potential to aid the understanding of biological processes and disease, including aging and cancer.
The “Chromatin Plasticity” Network brings together 13 academic and industrial research groups from 9 countries around the world to reveal novel mechanisms in the regulation of chromatin structure. Combining complementary approaches from disciplines as different as structural biology, mouse genetics, immunology, bioinformatics and drug design, the research partners are aiming to develop new approaches and tools to achieve a thorough understanding of chromatin plasticity, as well as to identify potential therapeutic targets for cancer and heart disease.
In this project, great emphasis is placed on training PhD students and postdoctoral researchers through collaborative exchanges, practical courses and visits within the network, contributing to the development of the next generation of European researchers.
Anna-Lynn Wegener | alfa
New insights into the information processing of motor neurons
22.02.2017 | Max Planck Florida Institute for Neuroscience
Wintering ducks connect isolated wetlands by dispersing plant seeds
22.02.2017 | Utrecht University
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
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09.02.2017 | Event News
22.02.2017 | Power and Electrical Engineering
22.02.2017 | Life Sciences
22.02.2017 | Innovative Products