The long molecules of DNA that carry our genetic information are wrapped up together with proteins into a dense complex called chromatin. The structure of chromatin is dynamic and varies according to different phases of a cell’s life, a phenomenon that is called chromatin plasticity. Chromatin structure plays a critical role in regulating our genes and research in this area has the potential to aid the understanding of biological processes and disease, including aging and cancer.
The “Chromatin Plasticity” Network brings together 13 academic and industrial research groups from 9 countries around the world to reveal novel mechanisms in the regulation of chromatin structure. Combining complementary approaches from disciplines as different as structural biology, mouse genetics, immunology, bioinformatics and drug design, the research partners are aiming to develop new approaches and tools to achieve a thorough understanding of chromatin plasticity, as well as to identify potential therapeutic targets for cancer and heart disease.
In this project, great emphasis is placed on training PhD students and postdoctoral researchers through collaborative exchanges, practical courses and visits within the network, contributing to the development of the next generation of European researchers.
Anna-Lynn Wegener | alfa
Single-stranded DNA and RNA origami go live
15.12.2017 | Wyss Institute for Biologically Inspired Engineering at Harvard
New antbird species discovered in Peru by LSU ornithologists
15.12.2017 | Louisiana State University
DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
11.12.2017 | Event News
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07.12.2017 | Event News
15.12.2017 | Power and Electrical Engineering
15.12.2017 | Materials Sciences
15.12.2017 | Life Sciences