Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study Suggests Cloned Mice Die Early

12.02.2002


Ethical considerations aside, a major issue in cloning is whether or not clones are as healthy as normally conceived animals. The evidence so far has been mixed. Some cloned cows have received clean bills of health, but Dolly suffers from premature arthritis, and many cloned animals are obese. According to a report published online today by the journal Nature Genetics, mice cloned from somatic cells fare particularly poorly. Indeed, the study found that cloned mice had significantly shorter life spans than did their naturally born counterparts.



Atsuo Ogura of the National Institute for Infectious Diseases in Tokyo, Japan, and colleagues cloned a dozen male mice and compared their development with that of animals with the same genetic background born through either natural mating or in vitro fertilization (IVF). The first cloned mouse died after 311 days, and 10 passed away within 800 days. In contrast, only one out of seven naturally conceived mice died within 800 days. The IVF mice also lived longer on average than did the cloned animals.

The researchers determined that the clones suffered from severe pneumonia and liver failure, ailments that did not affect the control mice. They further found reduced antibody production in a second group of cloned mice, suggesting that the immune systems of the cloned animals are less adept at fighting off infections than are those of regular animals. But because two of the clones are still alive and may achieve normal life spans, the scientists caution that clone longevity may depend on a multitude of factors, including genetic background and the type of cell utilized as a donor.

Sarah Graham | Scientific American

More articles from Life Sciences:

nachricht Antimicrobial substances identified in Komodo dragon blood
23.02.2017 | American Chemical Society

nachricht New Mechanisms of Gene Inactivation may prevent Aging and Cancer
23.02.2017 | Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut e.V. (FLI)

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

From rocks in Colorado, evidence of a 'chaotic solar system'

23.02.2017 | Physics and Astronomy

'Quartz' crystals at the Earth's core power its magnetic field

23.02.2017 | Earth Sciences

Antimicrobial substances identified in Komodo dragon blood

23.02.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>