Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Hope for arthritis stems from within

31.01.2006


Leeds bioengineers have developed an innovative technique for cartilage repair combining the self-healing powers of the body with stem cell science to help young people avoid debilitating knee problems and give hope to arthritis sufferers.



Current treatments of cartilage defects in the knee are expensive, have lengthy recovery times, and can even cause as much damage as good. “We’re responding to a real need,” said reader in bioengineering Dr Bahaa Seedhom.

“Orthopaedic surgeons are looking for ways to repair cartilage defects in young people which will delay, maybe even prevent, the need for total knee replacement.”


The bioengineers have invented a repair technique – and tools – that cut surgery times from two hours to ten minutes, and can have patients back on their feet within three weeks. The treatment involves a surgical technique called subchondral drilling, where holes are drilled into the bone beneath the cartilage in the damaged site, causing bleeding from the bone marrow, which stimulates stem cells to grow tissue within the damaged area. Surgeons then implant a felt-like pad, to encourage the cells to expand and grow into tissue.

As the treatment uses the body’s own stem cells, it is much cheaper than existing methods, where tissue is engineered outside the body and then implanted. The system has potential for widescale applications. “Initially young people with small defects will be most suitable for treatment, but once the system has been put through its paces it might well be used for larger defects in older arthritic patients,” said Dr Seedhom.

Dr Seedhom is joined on the project by Drs Toyoda, Luo, Lorrison and Michael Pullan from bioengineering. The arthritis research campaign has awarded the project £131,000 to explain the cartilage regeneration process, and Smith and Nephew have begun an evaluation programme to commercialise the technology for clinical use within four years.

Claire Jones | alfa
Further information:
http://www.leeds.ac.uk/medicine/musculoskeletal/bioengeneering.html
http://reporter.leeds.ac.uk/513/s2.htm

More articles from Life Sciences:

nachricht Unique genome architectures after fertilisation in single-cell embryos
30.03.2017 | IMBA - Institut für Molekulare Biotechnologie der Österreichischen Akademie der Wissenschaften GmbH

nachricht Transport of molecular motors into cilia
28.03.2017 | Aarhus University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Challenging European Research Project to Develop New Tiny Microscopes

The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.

To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

'On-off switch' brings researchers a step closer to potential HIV vaccine

30.03.2017 | Health and Medicine

Penn studies find promise for innovations in liquid biopsies

30.03.2017 | Health and Medicine

An LED-based device for imaging radiation induced skin damage

30.03.2017 | Medical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>