Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

U of MN researchers discover novel way estrogen affects the brain

20.05.2005


Hormone affects females, males differently



University of Minnesota researchers have demonstrated for the first time how estrogen affects learning and memory. They found that estrogen can activate particular glutamate receptors within the hippocampus, the brain region responsible for many aspects of learning and memory. Glutamate is the primary excitatory neurotransmitter in the brain, allowing for fast communication between neurons. By examining hippocampal neurons from rats, researchers also observed that estrogen only activated the processes related to learning and memory in the brains of female rats and not males. While it has been well documented that estrogen influences other behaviors beyond reproduction, including learning and memory, the mechanism has remained elusive. The findings of this research are in this week’s Journal of Neuroscience.

"We believe this is an important first step in understanding not just how estrogen affects learning and memory, but also a variety of non-reproductive behaviors," says Paul Mermelstein, Ph.D., assistant professor of neuroscience at the University of Minnesota and lead researcher. "Estrogen activation of glutamate receptors within other brain regions could also potentially account for the well-documented actions of this hormone on female motor control and pain sensation."


Marissa Boulware, a University of Minnesota neuroscience graduate student who performed the studies states, "Every day post-menopausal women face the dilemma of taking estrogens to improve their cognitive abilities, knowing it may pose a potential heath risk. By better understanding how estrogen acts upon our brain, one day we may develop novel therapies using non-steroidal drugs to mimic the specific actions of estrogen on processes related to learning and memory, affording the cognitive benefits of estrogen without any detrimental side effects."

Molly Portz | EurekAlert!
Further information:
http://www.umn.edu

More articles from Life Sciences:

nachricht A novel socio-ecological approach helps identifying suitable wolf habitats
17.02.2017 | Universität Zürich

nachricht New, ultra-flexible probes form reliable, scar-free integration with the brain
16.02.2017 | University of Texas at Austin

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Biocompatible 3-D tracking system has potential to improve robot-assisted surgery

17.02.2017 | Medical Engineering

Real-time MRI analysis powered by supercomputers

17.02.2017 | Medical Engineering

Antibiotic effective against drug-resistant bacteria in pediatric skin infections

17.02.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>