A new study sheds light on the response to infection in people with type 2 diabetes. These individuals develop diabetes associated with obesity. Findings from this study revealed that controlling a specific protein produced by the body, known as a cytokine, reduces the expression of other molecules and helps control inflammation. This is significant because many complications associated with diabetes trigger an inflammatory response. Right now, type 2 diabetes affects over 17 million people in the United States and impacts the health industry significantly on economic and individual levels .
Tumor necrosis factor (TNF), a type of cytokine, can cause inflammation and damage  in soft tissue infections, bite wounds and in periodontal disease. In a recent study published in the Journal of Investigative Dermatology, two groups of lab mice, one normal, the other diabetic, were injected with anaerobic bacteria, a germ present in “approximately one-third of bite wounds and … associated with the formation of abscesses and with relatively serious infections,” [3,4] to determine how type 2 diabetes affects the inflammatory response in surrounding tissue. Results from the tests demonstrated that the presence of diabetes prolongs inflammation. Following infection, the normal mice were able to rapidly resolve the ensuing inflammation within three days whereas the diabetic mice could not.
“It may be particularly important in diabetics to consider the impact that prolonged inflammation might have on the course of events,” states contributing author Dr. Dana T. Graves. According to the study, diabetics are particularly susceptible to the detrimental effects of infection associated with inflammatory cytokines. Further, inflammation can often be a precursor to complications such as cardiovascular disease and poor wound healing. Dr. Graves concludes, “If excess TNF in diabetics is inhibited, the tendency for prolonged inflammation is reduced.”
Sharon Agsalda | alfa
Complementing conventional antibiotics
24.05.2018 | Goethe-Universität Frankfurt am Main
Building a brain, cell by cell: Researchers make a mini neuron network (of two)
23.05.2018 | Institute of Industrial Science, The University of Tokyo
A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.
The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...
At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.
At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...
There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...
02.05.2018 | Event News
13.04.2018 | Event News
12.04.2018 | Event News
24.05.2018 | Ecology, The Environment and Conservation
24.05.2018 | Medical Engineering
24.05.2018 | Physics and Astronomy